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Description
The dataset contains a set of optical densities at 600 nm measured at microplate reader to determine the rate of fungal growth in the presence of Candida albicans homoserine O-acetyltransferase inhibitors. Antifungal activities were determined against several strains from Candida spp. and others by the modified M27-A3 method specified by the CLSI. We used strains from cell culture collections (C. albicans ATCC 10231, C. parapsilosis ATCC 22019, C. krusei ATCC 6258, C. glabrata ATCC 90030, C. krusei ATCC 6258, C. famata DSM 3428, C. rugosa DSM 2031, C. dublinensis CBS 7987 and Saccharomyces cerevisiae ATCC 9763) as well as C. albicans clinical strains.
The studies were financially supported from the project OPUS 20 financed by the National Science Centre (No. UMO-2020/39/B/NZ7/01519).
Dataset file
hexmd5(md5(part1)+md5(part2)+...)-{parts_count} where a single part of the file is 512 MB in size.Example script for calculation:
https://github.com/antespi/s3md5
File details
- License:
-
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CC BYAttribution - Raw data:
- Data contained in dataset was not processed.
Details
- Year of publication:
- 2022
- Verification date:
- 2022-07-05
- Dataset language:
- English
- Fields of science:
-
- chemical sciences (Natural sciences)
- DOI:
- DOI ID 10.34808/jhc2-ad98 open in new tab
- Funding:
- Verified by:
- Gdańsk University of Technology
Keywords
References
- dataset Overproduction of homoserine O-acetyltransferase (CaMet2p) native and His-tag versions.
- dataset Identification and cloning of C. albicans SC5314 genes encoding L-methionine biosynthetic pathway enzymes.
- dataset Inserts amplification for knockout cassette construction
- dataset Overproduction of CaMet15p native and His-tag versions.
- dataset L-Homoserine O-acetyltransferase (CaMet2p) activity and inhibition
- dataset Plasmids pMET2M1 and pMET15M1 with the SAT1 Flipper knockout cassette construction
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