Absorption spectroscopy setup for determination of whole human blood and blood–derived materials spectral characteristics

Maciej Wróbel; Marcin Gnyba; Daria Majchrowicz; Katarzyna Mitura; Katarzyna Karpienko

doi:10.1117/12.2201132

Absorption spectroscopy setup for determination of whole human blood and blood–derived materials spectral characteristics

Abstract

A dedicated absorption spectroscopy system was set up using tungsten-halogen broadband source, optical fibers, sample holder, and a commercial spectrometer with CCD array. Analysis of noise present in the setup was carried out. Data processing was applied to the absorption spectra to reduce spectral noise, and improve the quality of the spectra and to remove the baseline level. The absorption spectra were measured for whole blood samples, separated components: plasma, saline, washed erythrocytes in saline and human whole blood with biomarkers - biocompatible nanodiamonds (ND). Blood samples had been derived from a number of healthy donors. The results prove a correct setup arrangement, with adequate preprocessing of the data. The results of blood-ND mixtures measurements show no toxic effect on blood cells, which proves the NDs as a potential biocompatible biomarkers. © (2015) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.

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Authors (5)

Maciej Wróbel dr inż.
Marcin Gnyba dr hab. inż.
Daria Majchrowicz dr inż.
Katarzyna Mitura dr. inż
- Uniwersytet Koszaliński Inżynierii Biomedycznej
Katarzyna Karpienko dr inż.

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Category:: Conference activity
Type:: materiały konferencyjne indeksowane w Web of Science
Title of issue:: Conference on Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments strony 1 - 7
ISSN:: 0277-786X
Language:: English
Publication year:: 2015
Bibliographic description:: Wróbel M., Gnyba M., Majchrowicz D., Mitura K., Karpienko K..: Absorption spectroscopy setup for determination of whole human blood and blood–derived materials spectral characteristics, W: Conference on Photonics Applications in Astronomy, Communications, Industry, and High-Energy Physics Experiments, 2015, SPIE-INT SOC OPTICAL ENGINEERING,.
DOI:: Digital Object Identifier (open in new tab) 10.1117/12.2201132
Verified by:: Gdańsk University of Technology