Abstract

Despite antibiotics preventive treatment, before and after an implant implementation, risk of infection are real. These infections at the implant surface develop in a few months after applying them into the body. To prevent the development of bacteria and to reduce the risk of infection, implants coated with nanoparticles come into use. The Mechanical Department of the Technical University of Gdańsk carried out a research with the use of bone cement and metal nanoparticles used as an alternative to antibiotics [1-3]. Thus far, bone cement was used without supplement or with one or two drugs. These new experiments included pure bone cement with nanometals, without drugs. The titanium specimens were covered with such coating. Some specimens were inserted into rat's thigh for six weeks. Afterwars the implant was removed from the body and examined by means of scanning electron microscope. The results of the research were positive: there was a good adhesion of osteoblasts on the implant surface and there were no traces of infections. Biological researches have also been carried out. Boneless samples were places into a bacterial liquid generated by researcher (Registered patent no P409082). This liquid contains the five most common bacteria in the human body. Simultaneously mechanical and corrosion researches were carried out. A as result, this study concerns bone cement with nanoparticles, used as an alternative to antibiotics.

Authors (8)