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Metal-organic frameworks (MOFs)-based hybrid structures in developing glucose sensors

Abstract

Abstract The increasing number of diabetic individuals globally has highlighted the demand for nanostructured materials and devices for glucose detection, showcasing and demonstrating their importance in improving public health. Significant progress has correspondingly been made in the chemical modification of porous nanoparticles and nano-scale materials. Metal-organic frameworks (MOFs), due to their highly porous structure and catalytic properties, show great potential for glucose detection through oxidation mechanisms, which appears a key in fabrication of biosensors. However, limitations such as low stability and inadequate conductivity have convinced researchers that designing more complicated yet advanced MOF-based hybrid structures would be required for enhnaced glucose sensing and detection. This review provides an overview of the functions of MOFs in fabricating spectroscopic and electrochemical sensors for glucose detection. Moreover, it undertakes the mechanisms of enzymatic and nonenzymatic glucose sensors. Furthermore, other sensing-related applications of MOF-based materials in microfluidic systems, wearable devices, and advanced sensor technologies are briefly overviewed. Finally, challenges in designing MOF-based hybrid materials for glucose sensing and recommendations for future research are highlighted.

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Category:
Articles
Type:
artykuły w czasopismach
Published in:
CHEMICAL ENGINEERING JOURNAL no. 512,
ISSN: 1385-8947
Language:
English
Publication year:
2025
Bibliographic description:
Hosseini Sharifabad A., Safavi-Mirmahalleh S., Golshan M., Sienkiewicz M., Saeb M. R., Salami-Kalajahi M.: Metal-organic frameworks (MOFs)-based hybrid structures in developing glucose sensors// CHEMICAL ENGINEERING JOURNAL -Vol. 512,iss. 1 (2025), s.161513-
DOI:
Digital Object Identifier (open in new tab) 10.1016/j.cej.2025.161513
Sources of funding:
  • Free publication
Verified by:
Gdańsk University of Technology

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