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Optoelectronic investigation of nanodiamond interactions with human blood

Abstract

We present optoelectronic investigation of in vitro interactions of whole human blood with different nanodiamond biomarkers. Plasmo-chemical modifications of detonation nanodiamond particles gives the possibility for controlling their surface for biological applications. Optical investigations reveal the biological activity of nanodiamonds in blood dependent on its surface termination. We compare different types of nanodiamonds: commercial non-modified detonation nanodiamonds, and nanodiamonds modified by MW PACVD method with H2-termination, and chemically modified nanodiamond with O2-termination. The absorption spectra, and optical microscope investigations were conducted. The results indicate haemocompatibility of non-modified detonation nanodiamond as well as modified nanodiamonds, which enables their application for drug delivery, as well as sensing applications.

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Category:
Conference activity
Type:
materiały konferencyjne indeksowane w Web of Science
Title of issue:
Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII strony 1 - 2
ISSN:
0277-786X
Language:
English
Publication year:
2016
Bibliographic description:
Ficek M., Wróbel M., Wąsowicz M., Jędrzejewska-Szczerska M..: Optoelectronic investigation of nanodiamond interactions with human blood, W: Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIII, 2016, SPIE,.
DOI:
Digital Object Identifier (open in new tab) 10.1117/12.2208443
Verified by:
Gdańsk University of Technology

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