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Abstract
Immunomodulation is one of the significant therapeutic strategies. It includes both stimulation or suppression of the immune system by a variety of substances called immunomodulators, designed to regulate the immune response of the organism to infections of varying etiology. An example of such a substance is tuftsin (TKPA) 3 (Fig. (1)). Tuftsin is an endogenous immunomodulator of a wide spectrum of biological activity. Tetrapeptide 3 provides also antitumor, antimicrobial, anticoagulant and analgesic properties. In this paper, we presented tuftsin derivatives described over the years, its biological activity and potential clinical applications.
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- Copyright (2017 Bentham Science Publishers)
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- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
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CURRENT MEDICINAL CHEMISTRY
no. 24,
edition 42,
pages 1 - 18,
ISSN: 0929-8673 - Language:
- English
- Publication year:
- 2017
- Bibliographic description:
- Siebert A., Gensicka-Kowalewska M., Cholewiński G., Dzierzbicka K.: Tuftsin-Properties and Analogs// CURRENT MEDICINAL CHEMISTRY. -Vol. 24, iss. 42 (2017), s.1-18
- DOI:
- Digital Object Identifier (open in new tab) 10.2174/0929867324666170725140826
- Verified by:
- Gdańsk University of Technology
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