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dr hab Ewa Szymanska
Employment
- 1995 - present adiunkt/assistant professor at Wydział Farmaceutyczny
Research fields
- No data
Publications
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total: 33
Catalog Publications
Year 2022
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Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype
Publication -
Phenylalanine-Based AMPA Receptor Antagonist as the Anticonvulsant Agent with Neuroprotective Activity—In Vitro and In Vivo Studies
Publication
Year 2021
Year 2020
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Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry
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Discovery of phenylselenoether-hydantoin hybrids as ABCB1 efflux pump modulating agents with cytotoxic and antiproliferative actions in resistant T-lymphoma
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N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H3 receptor and cancer resistance proteins
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Search for ABCB1 Modulators Among 2-Amine-5-Arylideneimidazolones as a New Perspective to Overcome Cancer Multidrug Resistance
Publication
Year 2019
Year 2018
Year 2017
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Aryl- and heteroaryl-substituted phenylalanines as AMPA receptor ligands
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Pharmacological characterization and binding modes of novel racemic and optically active phenylalanine-based antagonists of AMPA receptors
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Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
Publication
Year 2016
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Design, synthesis and structure–activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands
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Efflux Pump Blockers in Gram-Negative Bacteria: The New Generation of Hydantoin Based-Modulators to Improve Antibiotic Activity
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Similarities and differences in affinity and binding modes of tricyclic pyrimido- and pyrazinoxanthines at human and rat adenosine receptors
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Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors
Publication
Year 2015
Year 2013
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Methods for the synthesis of xanthine-derived polycyclic fused systems
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Search for new tools to combat Gram-negative resistant bacteria among amine derivatives of 5-arylidenehydantoin
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Synthesis, biological activity and molecular modelling studies of tricyclic alkylimidazo-, pyrimido- and diazepinopurinediones
Publication
Year 2012
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Structural and Pharmacological Characterization of Phenylalanine-Based AMPA Receptor Antagonists at Kainate Receptors
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Synthesis and SAR-study for novel arylpiperazine derivatives of 5-arylidenehydantoin with α1-adrenoceptor antagonistic properties
Publication
Year 2011
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A New Phenylalanine Derivative Acts as an Antagonist at the AMPA Receptor GluA2 and Introduces Partial Domain Closure: Synthesis, Resolution, Pharmacology, and Crystal Structure
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Amine–alkyl derivatives of hydantoin: New tool to combat resistant bacteria
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Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin
Publication
Year 2010
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Crystallographic studies of (Z) and (E) isomers of 2-amino-5-(2-chlorobenzylidene)-1-methyl-1H-imidazol-4(5H)-one
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Synthesis of 5-arylidene-2-amino-4-azolones and evaluation of their anticancer activity
Publication
Year 2009
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3-Substituted phenylalanines as selective AMPA- and kainate receptor ligands
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Crystallographic and spectroscopic studies of 5-arylidene-2-amino-imidazol-4-ones
Publication
Year 2007
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The lipophilicity estimation of 5-arylidene derivatives of (2-thio)hydantoin with antimycobacterial activity
Publication
Year 2002
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Antimicrobial activity of 5-arylidene aromatic derivatives of hydantoin. Part 2
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Antimycobacterial activity of 5-arylidene aromatic derivatives of hydantoin
Publication
Year 2001
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