dr inż. Kamila Rząd
Employment
- Assistant professor at Department of Pharmaceutical Technology and Biochemistry
- Asystent at Department of Pharmaceutical Technology and Biochemistry
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Contact
- kamrzad@pg.edu.pl
Assistant professor
- Workplace
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Budynek B Wydz. Chemii
room 105 open in new tab - kamrzad@pg.edu.pl
Publication showcase
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Inhibitors of amino acids biosynthesis as antifungal agents
Fungal microorganisms, including the human pathogenic yeast and filamentous fungi, are able to synthesize all proteinogenic amino acids, including nine that are essential for humans. A number of enzymes catalyzing particular steps of human-essential amino acid biosynthesis are fungi specific. Numerous studies have shown that auxotrophic mutants of human pathogenic fungi impaired in biosynthesis of particular amino acids exhibit...
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Molecular targets for antifungals in amino acid and protein biosynthetic pathways
Fungi cause death of over 1.5 million people every year, while cutaneous mycoses are among the most common infections in the world. Mycoses vary greatly in severity, there are long-term skin (ringworm), nail or hair infections (tinea capitis), recurrent like vaginal candidiasis or severe, life-threatening systemic, multiorgan infections. In the last few years, increasing importance is attached to the health and economic problems...
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Versatility of putative aromatic aminotransferases from Candida albicans.
Amino acids constitute the key sources of nitrogen for growth of Candida albicans. In order to survive inside the host in different and rapidly changing environments, this fungus must be able to adapt via its expression of genes for amino acid metabolism. We analysed the ARO8, ARO9, YER152C, and BNA3 genes with regards to their role in the nutritional flexibility of C. albicans. CaAro8p is undoubtedly the most versatile enzyme...
Obtained scientific degrees/titles
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2018-10-09
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