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BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

ISSN:

0960-894X

eISSN:

1464-3405

Disciplines
(Field of Science):

  • biomedical engineering (Engineering and Technology)
  • medical biology (Medical and Health Sciences )
  • pharmacology and pharmacy (Medical and Health Sciences )
  • medical sciences (Medical and Health Sciences )
  • health sciences (Medical and Health Sciences )
  • food and nutrition technology (Agricultural sciences)
  • biotechnology (Natural sciences)
  • biological sciences (Natural sciences)
  • chemical sciences (Natural sciences)

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Year 2009
  • new analogues of agmatine with higher activity to imidazoline receptors
    Publication

    - BIOORGANIC & MEDICINAL CHEMISTRY LETTERS - Year 2009

    Opracowano syntezę nowych pochodnych imidazoliny, będących kompilacją struktury agmatyny i imidazoliny w wyniku zaprojektowanej przez nas drogi syntezy. Kluczowymi substratami w syntezie były pochodne 1,2,4 -triaminobutanu, otrzymane z chronionego kwasu glutaminowego. Otrzymane nowe pochodne imidazoliny wykazywały zróżnicowane powinowactwo do receptorów imidazolinowych I1, I2 oraz do receptorów alfa -adrenergicznych.

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