Gene Therapy and Regulation - Journal - Bridge of Knowledge

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Gene Therapy and Regulation

ISSN:

1388-9532

eISSN:

1568-5586

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Catalog Journals

Year 2011
  • Cardinal regenerative features of the MRL mouse
    Publication

    - Gene Therapy and Regulation - Year 2011

    In this review, we discuss recent studies relating to major features of adult MRL mouse biology that contribute to the regenerative responses seen. These include an increased inflammatory cell profile, a unique glycolytic metabolic state typically found during embryogenesis, and a cell cycle phenotype of DNA damage and G2/M arrest. These traits have been found in other mammalian and non-mammalian regenerative systems. How these...

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