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Description
The goal of the study was to obtain C. albicans Δmet2 (orf19.2618) strain using the SAT1-flipper method.
The deletion of the MET2 gene encoding homoserine O-acetyltransferase enable the assessment of the impact of this enzyme on the phenotype of cells, on the virulence of the strain, and allows to recognize the in vivo function of the tested proteins in L-methionine biosynthesis.
The studies were financially supported from the project OPUS 20 financed by the National Science Centre (No. UMO-2020/39/B/NZ7/01519).
Dataset file
C. albicans Δmet2 (orf19.2618) mutant strain construction.docx
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File details
- License:
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CC BYAttribution
Details
- Year of publication:
- 2025
- Verification date:
- 2025-02-19
- Creation date:
- 2025
- Dataset language:
- English
- Fields of science:
-
- chemical sciences (Natural sciences)
- biological sciences (Natural sciences)
- DOI:
- DOI ID 10.34808/c759-sw58 open in new tab
- Funding:
- Verified by:
- Gdańsk University of Technology
Keywords
References
- dataset Antifungal activity of L-homoserine O-acetyltransferase (CaMet2p) inhibitors.
- dataset Plasmids pMET2M1 and pMET15M1 with the SAT1 Flipper knockout cassette construction
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