Killing kinetics analysis of C-1311 derivative with octaarginine (Compound 1-R8) against Candida albicans - Open Research Data - Bridge of Knowledge

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Killing kinetics analysis of C-1311 derivative with octaarginine (Compound 1-R8) against Candida albicans

Description

The datasets contain the results of killing kinetics analysis of imidazoacridinone derivative and fluconazole against C. albicans ATCC 10231. The suspensions of Candida albicans ATCC 10231 cells (500 µL) in RPMI 1640 at cell density of 104 cells /mL were added to 500 µL of RPMI 1640 medium with various concentrations of the compounds, corresponding to 8 MIC, 4 MIC, 2 MIC, MIC, 1/2 MIC, vigorously shaken, and then incubated at 37°C for 60, 180 and 300 min. After an appropriate time of incubation, 10µL was withdrawn and spread on YPD agar plates. The number of colony-forming units (CFUs) was determined after overnight incubation of the plates at 37°C.

Dataset file

Killing kinetics analysis of R8C1.zip
214.4 MB, S3 ETag 0a783b9994b3a1109a8c0c1fc5957a53-1, downloads: 63
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download file Killing kinetics analysis of R8C1.zip

File details

License:
Creative Commons: by-nc-sa 4.0 open in new tab
CC BY-NC-SA
Non-commercial - Share-alike

Details

Year of publication:
2023
Verification date:
2023-09-28
Dataset language:
English
Fields of science:
  • chemical sciences (Natural sciences)
DOI:
DOI ID 10.34808/44p2-nz66 open in new tab
Funding:
Series:
Verified by:
Gdańsk University of Technology

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