Primary myelofibrosis - Male, 66 - Tissue image [11290630017293921] - Open Research Data - Bridge of Knowledge

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Primary myelofibrosis - Male, 66 - Tissue image [11290630017293921]

Description

This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

The detailed information about the patient, sample, and diagnosis are as follows:

Patient:

Age: 66

Clinical description: Patient with normocytic anemia Currently in a physical examination, splenomegaly. In additional studies on leucoerythroblastosis, LDH - 750 U / L. CALR mutation in molecular tests

Gender: Male

Diagnosis:

Classification: ICD-O_3.2

Classification code: CHRONIC MYELOPROLIFERATIVE DISORDERS

Diagnosis: Primary myelofibrosis

Result of the histopathological examination: Primary myelofibrosis Marrow with uneven cellularity, on average about 50%. The topography of the main lines of hemopoiesis is disturbed, the M: E ratio is 5: 1. Megakaryocytes more numerous in relation to the marrow cellularity, dysmorphic, irregularly arranged with the formation of several or several-cell clusters, some of the clusters are located peritellularly. The large forms with hypersegmentation of the nuclei dominate, some with a complete division of the nuclei, with the preserved N / C ratio. Significantly increased reticulin fibrosis (MF = 3) - Gomori Masson Trichrome - increased collagen fibrosis (G2)

Sample:

Material: FFPE

Collecting method: Bone marrow biopsy

Topography: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS

Organ: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS

Tissue: Bone marrow

Type of staining: positive/HE

Staining: Not applicable

Antibody: Not applicable

Technology:

Equipment: Pannoramic 250 3DHistech

Lens: 20x

Organization:

Source: Medical University Gdańsk

Dataset file

ea82cc7a-93f9-46ad-afb6-5ed68f55b60d
1.3 GB, S3 ETag , downloads: 22
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File details

License:
Creative Commons: by-nc-sa 4.0 open in new tab
CC BY-NC-SA
Non-commercial - Share-alike
Raw data:
Data contained in dataset was not processed.
Software:
CaseViewer 2.3

Details

Year of publication:
2021
Verification date:
2021-10-29
Creation date:
2021
Dataset language:
English
Fields of science:
  • medical sciences (Medical and Health Sciences )
DOI:
DOI ID 10.34808/7fpk-3893 open in new tab
Ethical papers:
NKBBN/421-306/2020
Verified by:
Medical University of Gdańsk

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