The aim of the project is to propose the numerical model of a human-occupied car crash against road safety barriers. The particular goal of the proposed research is to derive the mathematical description of a spine’s soft tissues behavior with the emphasis on the cervical part during highly nonlinear dynamic events, such as collisions against cable, steel or concrete barriers. The motivation for the research follows from the investigations of General Director for National Roads and Motorways (Generalna Dyrekcja Dróg Krajowych i Autostrad) into recommendations for design and usage of barriers mounted at Polish highways and expressways. Specifically, the most frequent injuries should be considered, that is those of the cervical spine. The knowledge about the potential range of injuries may have an impact on the recommendations for selection of barrier types in Poland. The original aspect of this project is to develop 2D and 3D anisotropic material law for modelling ligaments subjected to high speed dynamic loads as well as propose anisotropic viscoelastic material law for spinal cord.. Material parameters for soft tissues are to be acquired directly from the experiments performed on the human cervical spines. The experimental static tests will be done using surface imagining of strain variation system and dynamical test will be done using impulse load and high speed cameras. The numerical models will be validated by numerical simulations of experimental tests using authors’ FEM codes and LS-DYNA system. The results obtained during the project will be original on a global scale and will help in better understanding of mathematical and numerical description of cervical spine’s soft tissues during impact dynamics. The obtained conclusions may appear useful for medical personnel that assists the victims of real accidents by giving information about expected injuries depending on the conditions of the event. The proposed project requires an interdisciplinary research, conducted both by scientists from Gdańsk University of Technology and from Medical University of Gdańsk, into socially important aspects of human health and safety. The undertaken research will serve as the basis for scientific development and thus a step toward scientific degrees or titles for members of the research teams will be taken.