Shape and displacement optimization of gold nanorods in the killing chamber in order to phototermoablation processes

The project’s purpose is to investigate the heat and mass transfer processes in a micro-scale, ultimately bacteria-/viruses-contained chamber. The chamber would be undergone the photothermoablation process using gold nanorods. The main researchers’ challenges are to optimize the gold nanorods’ shape and the chamber itself in order to maximize the temperature increase and to deactivate the largest number of the bacteria at the same time. This occurs when the temperature exceeds a temperature value in the chamber. However, there is virtually impossible to measure the temperature inside the chamber due to the technical problems experimentally and therefore numerical methods emerge as a suitable technique to handle the topic and to compare with the experimental results at any surface. The so-applied methods’ advantages are its simplicity unquestionably, and enables to study many different cases included harmful biological issues, e.g. tumors placed in a liver, pancreas or even in blood .

Details

Project's acronym:

nanoHEATgold

Financial Program Name:

SONATA

Organization:

Narodowe Centrum Nauki (NCN) (National Science Centre)

Agreement:

UMO-2021/43/D/ST8/02504 z dnia 2022-11-15

Realisation period:

unknown - unknown

Project manager:

dr inż. Paweł Ziółkowski

Realised in:

Institute of Energy

External institutions participating in project:

gdański uniwersytet medyczny (Poland)

Request type:

National Research Programmes

Domestic:

Domestic project

Verified by:

Gdańsk University of Technology

Papers associated with that project

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total: 3

Year 2023

Energy conversion in systems-contained laser irradiated metallic nanoparticles - comparison of results from analytical solutions and numerical methods
Publication
- Acta Mechanica et Automatica - Year 2023
This work introduces the theoretical method of metallic nanoparticles’ (NPs’) heat and mass transfer where the particles are coated on a surface (base), together with considering the case wherein nanoparticles move freely in a pipe. In order to simulate the heat transfer, energy and radiative transfer equations are adjusted to the considered issue. NPs’ properties are determined following the nanofluidic theories, whereas absorption...

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Heat Transfer of the Multicolor-Laser-Sources-Irradiated Nanoparticles in Reference to Thermal Processes
Publication
- P. Radomski
- F. Zaccagnini
- P. Ziółkowski
- F. Petronella
- L. de Sio
- D. Mikielewicz
- Year 2023
Unlike the standard materials, metallic nanoparticles offer enhancing the heat convertion rate which implies the maximum and average temperature boost significantly in the considered system. The work’s purpose is to examine heat transfer in the metallic nanoparticles which have been deposited on a glassy substrate, enabling the nanostructures thermoablation. Furthermore, the functionalized substrate is irradiated with multicolor-laser-sources,...

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White light thermoplasmonic activated gold nanorod arrays enable the photo-thermal disinfection of medical tools from bacterial contamination
Publication
- F. Zaccagnini
- P. Radomski
- M. L. Sforza
- P. Ziółkowski
- S. Lim
- K. Jeong
- D. Mikielewicz
- N. P. Godman
- D. R. Evans
- J. E. Slagle... and 4 others
- Journal of Materials Chemistry B - Year 2023
The outspread of bacterial pathogens causing severe infections and spreading rapidly, especially among hospitalized patients, is worrying and represents a global public health issue. Current disinfection techniques are becoming insufficient to counteract the spread of these pathogens because they carry multiple antibiotic-resistance genes. For this reason, a constant need exists for new technological solutions that rely on physical...

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