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Abstract
The UvrA protein is a DNA-binding and damage-recognition enzyme which participates in the prokaryotic type nucleotide excision repair (NER) pathway. It has recently been noted that some bacterial genomes comprise additional uvrA genes which encode five distinct types of UvrA homologue. We investigated the sequences of over 2400 bacterial genomes and found 130 examples of bacteria containing uvrA 2 genes. The sequence analyses conducted on these UvrA homologues revealed that the previously established division of UvrA proteins might be based on some incorrect assumptions. In this paper, we present the reasons for our creation of a new division of UvrA homologues and a description of the four UvrA classes we have created.
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- Publication version
- Accepted or Published Version
- DOI:
- Digital Object Identifier (open in new tab) 10.5114/bta.2013.46439
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- Category:
- Articles
- Type:
- artykuły w czasopismach recenzowanych i innych wydawnictwach ciągłych
- Published in:
-
BioTechnologia
no. 94,
pages 54 - 56,
ISSN: 0860-7796 - Language:
- English
- Publication year:
- 2013
- Bibliographic description:
- Marszałkowska M., Olszewski M., Bil M., Kreft Ł.: A new division of bacterial UvrA homologues// BioTechnologia. -Vol. 94., iss. 1 (2013), s.54-56
- DOI:
- Digital Object Identifier (open in new tab) 10.5114/bta.2013.46439
- Verified by:
- Gdańsk University of Technology
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