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Assessing Acute Toxicity and Endocrine Disruption Potential of Selected Packages Internal Layers Extracts
Abstract
The focus of the present study is migration of toxic substances from food contact materials and its actual influence on the health of the final consumer. Two food packagings (metal cans, TetraPack®) and five simulants medias (water, ethanol, acetic acid, DMSO, artificial saliva) were selected for simulation studies. For assessment of acute toxicity and endocrine disruption potential of extract samples, two biotests (Microtox® and XenoScreen YES/YAS) were performed. Multi-factor analysis of variation (MANOVA) was used to evaluate the effects of the three main factors - solvent, temperature, contact time and their interactions on the respected dependent variable (acute toxicity or estrogen disruption potential).
Authors (5)
-
Galina Yotova
- University of Sofia
-
Stefan Tsakovski
- University of Sofia
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Details
- Category:
- Conference activity
- Type:
- publikacja w wydawnictwie zbiorowym recenzowanym (także w materiałach konferencyjnych)
- Title of issue:
- ICTFP 2018: 20th International Conference on Toxicants in Food Packaging strony 2678 - 2683
- Language:
- English
- Publication year:
- 2018
- Bibliographic description:
- Jatkowska N., Kudłak B., Yotova G., Tsakovski S., Namieśnik J.: Assessing Acute Toxicity and Endocrine Disruption Potential of Selected Packages Internal Layers Extracts// ICTFP 2018: 20th International Conference on Toxicants in Food Packaging/ Madryd: , 2018, s.2678-2683
- Verified by:
- Gdańsk University of Technology
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