Search
Abstract
Bile Salts (BS) are responsible for stimulating lipid digestion in our organism. Gut microbiota are responsible for the deconjugation process of primary conjugated to secondary unconjugated BS. We use two structurally distinct BS and characterize the rate of lipolysis as a compound parameter. A static in-vitro digestion model as well as meta-analysis of literature data has been performed to determine the most influential factors affecting the lipid digestion process. The results demonstrate that lipolysis of emulsions using conjugated BS (NaTC, FFA = 60.0 %, CMC in SIF = 5.58 mM, MSR of linoleic acid = 0.21, rate of adsorption = -0.057 mN/m.s) enhances the release of FFA compared to deconjugated BS (NaDC, FFA = 49.5 %, CMC in SIF = 2.49 mM, MSR of linoleic acid = 0.16 rate of adsorption = -0.064 mN/m.s). These results indicate that conjugation plays an important role in controlling the rate of lipolysis in our organism which can be in turn, tuned by the microflora composition of our gut, ultimately controlling the rate of deconjugation of the BS.
Citations
-
1
CrossRef
-
0
Web of Science
-
1
Scopus
Authors (7)
-
Julia Maldonado-Valderrama
- University of Granada
-
Teresa Del Castillo Santaella
- University of Granada
-
Yuanqi Lu
- University of Dezhou
Cite as
Full text
full text is not available in portal
Keywords
Details
- Category:
- Articles
- Type:
- artykuły w czasopismach
- Published in:
-
FOOD RESEARCH INTERNATIONAL
no. 184,
ISSN: 0963-9969 - Language:
- English
- Publication year:
- 2024
- Bibliographic description:
- Łozińska N., Maldonado-Valderrama J., Del Castillo Santaella T., Zhou Y., Martysiak-Żurowska D., Lu Y., Jungnickel C.: Bile conjugation and its effect on in vitro lipolysis of emulsions// FOOD RESEARCH INTERNATIONAL -, (2024), s.114255-
- DOI:
- Digital Object Identifier (open in new tab) 10.1016/j.foodres.2024.114255
- Sources of funding:
-
- Statutory activity/subsidy
- Verified by:
- Gdańsk University of Technology
seen 71 times
Recommended for you
Bile salts in digestion and transport of lipids
- A. Macierzanka,
- A. Torcello-Gómez,
- C. Jungnickel
- + 1 authors
The bile salt/phospholipid ratio determines the extent of in vitro intestinal lipolysis of triglycerides: Interfacial and emulsion studies
- K. Kłosowska,
- T. Del Castillo Santaella,
- J. Maldonado-Valderrama
- + 1 authors
Interfacial behaviour of human bile and its substitution for in vitro lipolysis studies
- D. Dulko,
- I. Kłosowska-Chomiczewska,
- T. del Castillo-Santaella
- + 6 authors