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Efficient Method for the Synthesis of Functionalized Basic Maleimides

Abstract

A three-step procedure involving Diels-Alder condensation of maleic anhydride with furane, formation of N-substituted imide upon reaction with appropriate diamine and a final retro Diels-Alder regeneration of the maleic carbon-carbon double bond is proposed for an unequivocal synthesis of N-substituted basic maleimides. The novel method is characterized by mild reaction conditions, easy work-up, high yields and no need for additional catalysis.

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DOI:
Digital Object Identifier (open in new tab) 10.1002/jhet.1651
License
Copyright (2013 HeteroCorporation)

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Category:
Articles
Type:
artykuł w czasopiśmie wyróżnionym w JCR
Published in:
JOURNAL OF HETEROCYCLIC CHEMISTRY no. 51, edition 4, pages 999 - 1003,
ISSN: 0022-152X
Language:
English
Publication year:
2014
Bibliographic description:
Salewska N., Milewska M.: Efficient Method for the Synthesis of Functionalized Basic Maleimides// JOURNAL OF HETEROCYCLIC CHEMISTRY. -Vol. 51, iss. 4 (2014), s.999-1003
DOI:
Digital Object Identifier (open in new tab) 10.1002/jhet.1651
Verified by:
Gdańsk University of Technology

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