Full scattering profile of circular optical phantoms mimicking biological tissue - Publication - Bridge of Knowledge

Search

Full scattering profile of circular optical phantoms mimicking biological tissue

Abstract

Human tissue is one of the most complex optical media since it is turbid and nonhomogeneous. In our poster, we suggest a new type of skin phantom and an optical method for sensing physiological tissue condition, basing on the collection of the ejected light at all exit angles, to receive the full scattering profile. Conducted experiments were carried out on an unique set-up for noninvasive encircled measurement. Set-up consisted of a laser, a photodetector and new tissues-like phantoms made with a polyvinyl chloride-plastisol (PVCP), silicone elastomer polydimethylsiloxane (PDMS) and PDMS with glycerol mixture. Our method reveals an isobaric point, which is independent of the optical properties. Furthermore, we present the angular distribution of cylindrical phantoms, in order to sense physiological tissue state.

Citations

  • 0

    CrossRef

  • 0

    Web of Science

  • 1

    Scopus

Cite as

Full text

download paper
downloaded 102 times
Publication version
Accepted or Published Version
License
Copyright (2017 SPIE)

Keywords

Details

Category:
Conference activity
Type:
materiały konferencyjne indeksowane w Web of Science
Title of issue:
Proceedings Volume 10077, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV strony 1 - 9
Language:
English
Publication year:
2017
Bibliographic description:
Feder I., Wróbel M., Duadi H., Fixler D., Szczerska M..: Full scattering profile of circular optical phantoms mimicking biological tissue, W: Proceedings Volume 10077, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIV, 2017, ,.
DOI:
Digital Object Identifier (open in new tab) 10.1117/12.2250652
Bibliography: test
  1. Tuchin, V.V., "Light scattering study of tissues," Physics-Uspekhi 40(5), 495 (1997). open in new tab
  2. Schmitt, J., A. Knüttel, and R. Bonner, "Measurement of optical properties of biological tissues by low-coherence reflectometry," Applied Optics 32(30), 6032- 6042 (1993). open in new tab
  3. Lee, P., W. Gao, and X. Zhang, "Performance of single-scattering model versus multiple-scattering model in the determination of optical properties of biological tissue with optical coherence tomography," Applied optics 49(18), 3538-3544 (2010). open in new tab
  4. Levitz, D., et al., "Determination of optical scattering properties of highly-scattering media in optical coherence tomography images," Optics express 12(2), 249-259 (2004). open in new tab
  5. Schmitt, J. and A. Knüttel, "Model of optical coherence tomography of heterogeneous tissue," JOSA A 14(6), 1231-1242 (1997). open in new tab
  6. Thrane, L., H.T. Yura, and P.E. Andersen, "Analysis of optical coherence tomography systems based on the extended Huygens-Fresnel principle," JOSA A 17(3), 484-490 (2000). open in new tab
  7. Pickering, J.W., et al., "Double-integrating-sphere system for measuring the optical properties of tissue," Applied optics, 32(4), 399-410 (1993). open in new tab
  8. Arridge, S.R., M. Cope, and D. Delpy, The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis," Physics in medicine and biology, 37(7), 1531 (1992). open in new tab
  9. Spinelli, L., et al., "Determination of reference values for optical properties of liquid phantoms based on Intralipid and India ink," Biomedical Optics Express, 5(7), 2037- 2053 (2014). open in new tab
  10. Jacques, S.L., "Optical properties of biological tissues: a review. Physics in medicine and biology," Physics in medicine and biology, 58(11), R37 (2013). open in new tab
  11. Lu, G. and B. Fei, "Medical hyperspectral imaging: a review," Journal of biomedical optics, 19(1), 010901-010901 (2014). open in new tab
  12. Duadi, H., I. Feder, and D. Fixler, "Linear dependency of full scattering profile isobaric point on tissue diameter," Journal of biomedical optics 19(2), 026007- 026007 (2014). open in new tab
  13. Feder, I., H. Duadi, and D. Fixler "Experimental system of the full scattering profile of circular phantoms," Biomed. Opt. Express 6(8) 2877-2886, (2015). open in new tab
  14. Feder, I., H. Duadi, T. Dreifuss and D. Fixler "The influence in the full scattering profile from cylindrical tissues following changes in vessels diameter: experimental evidence for the shielding effect," Journal of biophotonics (2015). open in new tab
  15. Feder, I., et al., "Experimental results of full scattering profile from finger tissue-like phantom," Biomed. Opt. Express 7, 4695-4701 (2016) open in new tab
  16. Wróbel, M.S. et al., "Nanoparticle-free tissue-mimicking phantoms with intrinsic scattering," Biomed. Opt. Express 7, 2088-2094 (2016). open in new tab
  17. Wróbel, M.S., et al. "Multi-layered tissue head phantoms for noninvasive optical diagnostics," J. Innov. Opt. Health Sci., 08, 1541005 (2015). open in new tab
  18. Wróbel, M.S., et al. "Measurements of fundamental properties of homogeneous tissue phantoms," J. Biomed. Opt., 20(4), 045004 (2015) open in new tab
  19. Ankri, R., H. Taitelbaum, and D. Fixler, "On Phantom experiments of the photon migration model in tissues," The Open Optics Journal 5, 28-32 (2011). open in new tab
  20. Ankri, R., H. Duadi, and D. Fixler. "A new diagnostic tool based on diffusion reflection measurements of gold nanoparticles," SPIE BiOS. (2012). open in new tab
  21. Ankri, R., "Non Invasive Optical Technique for the Investigation of Tissue Structure and Physiology," Ph.D. Thesis, 4-11 (2012). open in new tab
  22. Friebel, M., et al., "Determination of optical properties of human blood in the spectral range 250to1100nm using Monte Carlo simulations with hematocrit- dependent effective scattering phase functions," Journal of biomedical optics 11(3), 034021-034021-10 (2006). open in new tab
  23. Reif, R., O. A'Amar, AND I. J Bigio, "Analytical model of light reflectance for extraction of the optical properties in small volumes of turbid media," Applied optics 46(29) 7317-7328 (2007). open in new tab
  24. Jacques, SL, BW Pogue, "Tutorial on diffuse light transport," Journal of biomedical optics 13(4) 041302-19 (2008). open in new tab
  25. Duadi, H., D. Fixler, and R. Popovtzer. "Dependence of light scattering profile in tissue on blood vessel diameter and distribution: a computer simulation study," Journal of biomedical optics 18(11), 111408-111408 (2013). open in new tab
  26. Duadi, H., Nitzan M. and D. Fixler. "Simulation of oxygen saturation measurement in a single blood vein," Optics Letters (to be published). open in new tab
  27. M. S. Wróbel, M. Jedrzejewska-Szczerska, S. Galla, L. Piechowski, M. Sawczak, A. P. Popov, A. V. Bykov, V. V. Tuchin, and A. Cenian, "Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy," Journal of Biomedical Optics 20, 85003 (2015). open in new tab
  28. M. Jędrzejewska-Szczerska, M. S. Wróbel, S. Galla, A. P. Popov, A. V. Bykov, V. V. Tuchin, and A. Cenian, "Investigation of photothermolysis therapy of human skin diseases using optical phantoms," SPIE Proc. 9447, 944715 (2015). open in new tab
  29. S. Hyttel-Sorensen, S. Kleiser, M. Wolf, and G. Greisen, "Calibration of a prototype NIRS oximeter against two commercial devices on a blood-lipid phantom," Biomed Opt Express 4, 1662-1672 (2013). open in new tab
  30. V. O. Korhonen, T. S. Myllyla, M. Y. Kirillin, A. P. Popov, A. V. Bykov, A. V. Gorshkov, E. A. Sergeeva, M. Kinnunen, and V. Kiviniemi, "Light Propagation in NIR Spectroscopy of the Human Brain," IEEE Journal of Selected Topics in Quantum Electronics 20, 1-10 (2014). open in new tab
  31. D. Fixler, R. Tirosh, N. Zurgil, and M Deutsch, "Tracing apoptosis and stimulation in individual cells by fluorescence intensity and anisotropy decay ," Journal of biomedical optics, 19(3), 034007-0340078 (2005). open in new tab
  32. D. Fixler, R. Tirosh, T. Zinman, A. Shainberg, and M Deutsch, " Differential aspects in ratio measurements of [Ca 2+]i relaxation in cardiomyocyte contraction following various drug treatments ," Cell Calcium 31(6), 279-287 (2002). open in new tab
Verified by:
Gdańsk University of Technology

seen 100 times

Recommended for you

Meta Tags