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Abstract
Lung microangiopathy is a little known negative influence of diabetes mellitus on the functioning of the lungs. In current medical practice lung microangiopathy is diagnosed by comparing two measurements of lung diffusing capacity - one with the subject standing and one with the subject lying. The necessity to take two measurements is inconvenient. In lung microangiopathy we observe a reduction of diffusing capacity, lung flow and volume. Diabetes is a chronic illness that can lead to diabetic angiopathy, a disease of the blood vessels (arteries, veins and capillaries). The technique of lung pCT involves the intravenous injection of a non-iodinated contrast agent and the sequential scanning of the diagnosed region of the chest. There are a number of pulmonary perfusion parameters, calculated pixel by pixel on the basis of raw CT data, which are next analysed in order to reveal differences between the normal and altered tissue. The most useful perfusion parameters are: blood volume (BV), blood flow (BF), mean transit time (MTT), time to peak (TTP) and permeability surface (PS) (Kuziemski et al, 2011).The diagnosis of pulmonary function has to be based on indirect results, such as diffusing capacity, spirometry and pCT because direct assessment is difficult.
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- Category:
- Monographic publication
- Type:
- rozdział, artykuł w książce - dziele zbiorowym /podręczniku w języku o zasięgu międzynarodowym
- Title of issue:
- Lung diseases - selected state of the art reviews strony 603 - 624
- Language:
- English
- Publication year:
- 2012
- Bibliographic description:
- Kalicka R., Kuziemski K.: Novel methods for diagnosis of pulmonary microangiopathy in diabetes mellitus// Lung diseases - selected state of the art reviews/ ed. ed. E. M. Irusen. : InTech, 2012, s.603-624
- Verified by:
- Gdańsk University of Technology
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