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Abstract
Abstract: A one pot synthesis for preparation of 1,4-disubstituted-2-oxo-azetidine-3-carboxylic acid amides was developed. 5-(α-N-substituted-amino-α'-hydroxy)methylene Meldrum's acids act as a source of ketenes that react with aldimines in boiling toluene to give b-lactams with retro-amid side chain.
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- Publication version
- Accepted or Published Version
- DOI:
- Digital Object Identifier (open in new tab) 10.1055/s-0030-1258966
- License
- Copyright (2011 Georg Thieme Verlag Stuttgart, New York)
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- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
-
SYNTHESIS-STUTTGART
pages 69 - 72,
ISSN: 0039-7881 - Language:
- English
- Publication year:
- 2011
- Bibliographic description:
- Janikowska K., Pawelska N., Makowiec S.: One-Step Synthesis of b-Lactams with Retro-Amide Side Chain// SYNTHESIS-STUTTGART. -, nr. iss. 1 (2011), s.69-72
- Verified by:
- Gdańsk University of Technology
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