Photonic sensor to detect rapid changes in CRP levels

Małgorzata Szczerska; Monika Kosowska; Roman Viter; Paweł Wityk

doi:10.1002/jbio.202200213

Photonic sensor to detect rapid changes in CRP levels

Abstract

One of the most important biomarkers used to determine inflammation is C-reactive protein (CRP). Its level, when it is within the range that does not define inflammation, informs about the risk of cardiovascular events. If the norm is exceeded and inflammation is detected in the body, CRP level can increase 1000 times within a few hours. The type of infection can also be determined based on the level of elevated CRP. All this makes CRP a very important element of diagnostics. A sensor based on low coherence interference is presented. Preliminary studies have shown that its sensitivity is 5.65 μg/L and the measurement time is short, <10 min. The entire system is built of commercially available components, which allow production cost minimalization. In addition, the user-friendly operation allows it to be operated by unqualified people. Due to these features, our solution is a promising alternative to commercially used enzyme-linked immunosorbent assay, which needs trained personnel to perform time-consuming measurement procedures.

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Publication version: Accepted or Published Version
License: Copyright (2022 Wiley-VCH GmbH.)

Keywords

PHOTONIC SENSOR

Details

Category:

Articles

Type:

artykuły w czasopismach

Published in:

Journal of Biophotonics no. 16,
ISSN: 1864-063X

Language:

English

Publication year:

2023

Bibliographic description:

Szczerska M., Kosowska M., Viter R., Wityk P.: Photonic sensor to detect rapid changes in CRP levels// Journal of Biophotonics -Vol. 16,iss. 1 (2023),

DOI: