Short Term Monitor of Photodegradation Processes in Ranitidine Hydrochloride Observed by FTIR and ATR FTIR - Publication - Bridge of Knowledge

Search

Short Term Monitor of Photodegradation Processes in Ranitidine Hydrochloride Observed by FTIR and ATR FTIR

Abstract

The effects of degradation of ranitidine hydrochloride exposed to UVB radiation (l = 310 nm) and oxygen in a weathering chamber were studied by Fourier Transform Infrared spectroscopy (FTIR) and Attenuated Total Reflectance Fourier Transform 
Infrared spectroscopy (ATR-FTIR). ATR-FTIR profile indicated that the degradation was spatially heterogeneous. Significant amounts of photoproducts were detected only in a directly irradiated layer. Major damage/change was reflected in the appearance
of broad, extended group of signals near the wavenumber 3600-3200 cm-1 or/and 3500-3400 cm-1. We examined whether FTIR-ATR technique is a great tool to observe the simplest and the first changes on the surface of a substance in powder.

Authors (2)

Cite as

Full text

full text is not available in portal

Details

Category:
Magazine publication
Type:
Magazine publication
Published in:
JOURNAL OF FOOD AND DRUG ANALYSIS no. 17, edition 5, pages 342 - 347,
ISSN: 1021-9498
Publication year:
2009
Verified by:
No verification

seen 55 times

Recommended for you

Meta Tags