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Synthesis of new antrapyridazone derivatives - a novel group of anticancer agents active on a multidrugresistant(MDR) tumor cell lines
Abstract
Novel antrapyridazone derivatives were synthesized and biologically evaluated in order tobroaden the data on structure-activity relationship of this class of cytostatics. Recent literaturedata prove that acetamides react better with aryl chlorides. A new approach based onintroduction of other amides form into aromatic ring in Ullmann was tested. This new methodcould give better yields and make purification step more convenient.
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- Category:
- Conference activity
- Type:
- publikacja w wydawnictwie zbiorowym recenzowanym (także w materiałach konferencyjnych)
- Title of issue:
- 13th International Symposium of Students and Young Mechanical Engineers :''Advances in Chemical and Mechanical Engineering'', Gdańsk, 20th-22nd May 2010 strony 318 - 324
- Language:
- English
- Publication year:
- 2010
- Bibliographic description:
- Punda P.: Synthesis of new antrapyridazone derivatives - a novel group of anticancer agents active on a multidrugresistant(MDR) tumor cell lines// 13th International Symposium of Students and Young Mechanical Engineers :''Advances in Chemical and Mechanical Engineering'', Gdańsk, 20th-22nd May 2010/ ed. ed. C. Fijało. - Gdansk University of Technology. Gdańsk: GUT, 2010, s.318-324
- Verified by:
- Gdańsk University of Technology
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