Search
t-SNE Highlights Phylogenetic and Temporal Patterns of SARS-CoV-2 Spike and Nucleocapsid Protein Evolution
Abstract
We propose applying t-distributed stochastic neighbor embedding to protein sequences of SARS-CoV-2 to construct, visualize and study the evolutionary space of the coronavirus. The basic idea is to explore the COVID-19 evolution space by using modern manifold learning techniques applied to evolutionary distances between variants. Evolutionary distances have been calculated based on the structures of the nucleocapsid and spike proteins.
Citations
-
1
CrossRef
-
0
Web of Science
-
1
Scopus
Authors (9)
-
Gaik Tamazian Dr.
- Peter the Great Saint Petersburg Polytechnic University
-
Andrey Komissarov Dr.
- Smorodintsev Research Institute of Influenza, St. Petersburg
-
Dmitry Kobak Dr.
- University of Tübingen, Tübingen, Germany
-
Dmitry Polyakov Dr.
- Higher School of Economics
-
Evegeny Andronov Dr.
- All-Russia Research Institute for Agricultural Microbiology, Russian Academy of Sciences
-
Sergei Nechaev Prof
- LPTMS, Universitè Paris Saclay
-
Yuri Porozov Dr.
- The Center of Bio- and Chemoinformatics, I.M. Sechenov First Moscow State Medical University
-
Eugene Stepanov Prof.
- Scuola Normale Superiore, Pisa
Cite as
Full text
full text is not available in portal
Keywords
Details
- Category:
- Monographic publication
- Type:
- rozdział, artykuł w książce - dziele zbiorowym /podręczniku w języku o zasięgu międzynarodowym
- Language:
- English
- Publication year:
- 2022
- Bibliographic description:
- Tamazian G., Komissarov A., Kobak D., Polyakov D., Andronov E., Nechaev S., Kryzhevich S., Porozov Y., Stepanov E.: t-SNE Highlights Phylogenetic and Temporal Patterns of SARS-CoV-2 Spike and Nucleocapsid Protein Evolution// / : , 2023,
- DOI:
- Digital Object Identifier (open in new tab) 10.1007/978-3-031-23198-8_23
- Sources of funding:
-
- Free publication
- Verified by:
- Gdańsk University of Technology
seen 62 times
Recommended for you
Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site
- U. Kalathiya,
- M. Padariya,
- M. Mayordomo
- + 11 authors
2020
Neural Networks, Support Vector Machine and Genetic Algorithms for Autonomous Underwater Robot Support
- J. Balicki,
- J. Masiejczyk,
- P. Przybecki
- + 1 authors
2014