Search results for: SERTRALINE HYDROCHLORIDE - Bridge of Knowledge

Search results for: SERTRALINE HYDROCHLORIDE

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Thermodynamic Studies of Interactions between Sertraline Hydrochloride and Randomly Methylated β-Cyclodextrin Molecules Supported by Circular Dichroism Spectroscopy and Molecular Docking Results
Publication
- S. Belica-Pacha
- M. Daśko
- V. Buko
- I. Zavodnik
- K. Miłowska
- M. Bryszewska
- INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2021
The interaction between sertraline hydrochloride (SRT) and randomly methylated β-cyclodextrin (RM β CD) molecules have been investigated at 298.15 K under atmospheric pressure. The method used—Isothermal Titration Calorimetry (ITC) enabled to determine values of the thermodynamic functions like the enthalpy (DH), the entropy (DS) and the Gibbs free energy (DG) of binding for the examined system. Moreover, the stoichiometry coefficient...

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