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Search results for: SKIN
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Skin Research
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Neuroendocrinology of the skin
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Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
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SKIN PHARMACOLOGY AND PHYSIOLOGY
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SKIN RESEARCH AND TECHNOLOGY
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Journal of Skin Cancer
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Clinical Skin Cancer
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Skin therapy letter
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Skin Appendage Disorders
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Melatonin, mitochondria, and the skin
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Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy
PublicationSkin lesions are commonly treated using laser heating. However, the introduction of new devices into clinical practice requires evaluation of their performance. This study presents the application of optical phantoms for assessment of a newly developed 975-nm pulsed diode laser system for dermatological purposes. Such phantoms closely mimic the absorption and scattering of real human skin (although not precisely in relation to...
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Polydopamine Biomaterials for Skin Regeneration
PublicationDesigning biomaterials capable of biomimicking wound healing and skin regeneration has been receiving increasing attention recently. Some biopolymers behave similarly to the extracellular matrix (ECM), supporting biointerfacial adhesion and intrinsic cellular interactions. Polydopamine (PDA) is a natural bioadhesive and bioactive polymer that endows high chemical versatility, making it an exciting candidate for a wide range of...
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Corticotropin releasing hormone and the skin
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Polymers for burn dressings and skin substitutes
PublicationSkin burns belong to the group of the most complex injuries due to convoluted skin structure which includes nerve cells, muscles, sweat and sebaceous glands and blood vessels. Both on the market and at the research stage, there are many different dressing and skin substitutes proposals that utilize various materials and active substances. This chapter focuses on summarizing and describing the most popular polymer-based commercial...
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Advances in Skin & Wound Care
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SKIN: Journal of Cutaneous Medicine
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Thermal imaging and modelling of burned skin
PublicationW artykule przedstawiono wyniki eksperymentów in-vivo na zwierzętach w diagnostyce oparzeń z wykorzystaniem metod obrazowania termicznego w podczerwieni. Wyniki skorelowano z rezultatami otrzymanymi w symulacjach numerycznych tkanki skóry.
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Melatonin in the skin: synthesis, metabolism and functions
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On the Role of Melatonin in Skin Physiology and Pathology
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Vitamin D in the skin physiology and pathology.
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Non-lipophilic mycobiota of human skin
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Neotenic phenomenon in gene expression in the skin of Foxn1- deficient (nude) mice - a projection for regenerative skin wound healing
PublicationMouse fetuses up to 16 day of embryonic development and nude (Foxn1- deficient) mice are examples of animals that undergo regenerative (scar-free) skin healing. The expression of transcription factor Foxn1 in the epidermis of mouse fetuses begins at embryonic day 16.5 which coincides with the transition point from scar-free to scar-forming skin wound healing. In the present study, we tested the hypothesis that Foxn1 expression...
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Synthetic lipopeptides as potential topical therapeutics in wound and skin care: in vitro studies of permeation and skin cells behaviour
PublicationSeveral Gly-His-Lys analogues were obtained to investigate their antimicrobial properties. Three lipophilic analogues with the structure numbering 1b, 2b, 4b, exhibit significant effect against bacteria and were selected for in vitro evaluation of skin cells behaviour. In the present studies, an in vitro model of wound repair, proliferative cell staining, and tracking of living cells were used. Cell proliferation and cell migration,...
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Green Polymer Nanocomposites for Skin Tissue Engineering
PublicationFabrication of an appropriate skin scaffold needs to meet several standards related to the mechanical and biological properties. Fully natural/green scaffolds with acceptable biodegradability, biocompatibility, and physiological properties quite often suffer from poor mechanical properties. Therefore, for appropriate skin tissue engineering and to mimic the real functions, we need to use synthetic polymers and/or additives as complements...
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Real-Time Skin Quality Assessment System
PublicationThis thesis presents a real-time skin assessment system with the main aim of detecting inflammatory acne lesions and tracking skin conditions. A facial acne lesion detection algorithm was developed, using a pre-trained YOLOv8 model for lesion detection and a Mediapipe detector for face detection. The proposed solution aims to create a system used in smart mirrors to help users self-monitor and monitor their skin condition in real...
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Innate Lymphoid Cells in Skin Homeostasis and Malignancy
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Steroidogenesis in the skin: Implications for local immune functions
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CRH functions as a growth factor/cytokine in the skin
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Differentiation of Keratinocytes Modulates Skin HPA Analog
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Local Melatoninergic System as the Protector of Skin Integrity
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Novel vitamin D photoproducts and their precursors in the skin
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Multilayer thermal model of healty and burned skin
PublicationW pracy przedstawiono spójny model cieplny skóry wraz z tkankami podskórnymi, na podstawie pomiarów "in vitro" na świni domowej. Model uwzględnia rozkład temperatury, przewodności cieplnej oraz efuzyjności i dyfuzyjności cieplnej w funkcji głębokości, zarówno dla skóry zdrowej jak i oparzonej.
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A ring-based probe for determination of the skin conductivity
PublicationW pracy przedstawiono konstrukcję sondy do pomiarów przewodności skóry wstanie oparzenia.
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Neural Architecture Search for Skin Lesion Classification
PublicationDeep neural networks have achieved great success in many domains. However, successful deployment of such systems is determined by proper manual selection of the neural architecture. This is a tedious and time-consuming process that requires expert knowledge. Different tasks need very different architectures to obtain satisfactory results. The group of methods called the neural architecture search (NAS) helps to find effective architecture...
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Does the Aberrant Expression of CD2 and CD25 by Skin Mast Cells Truly Correlate with Systemic Involvement in Patients Presenting with Mastocytosis in the Skin?
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Experimental Paper. Activity of essential oils against Staphylococcus aureus strains isolated from skin lesions in the course of staphylococcal skin infections
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Polylysine for Skin Regeneration: A Review of Recent Advances and Perspectives
PublicationThere have been several attempts to find promising biomaterials for skin regeneration, among which polylysine (a homopolypeptide) has shown benefits in the regeneration and treatment of skin disorders. This class of biomaterials has shown exceptional abilities due to their macromolecular structure. Polylysine-based biomaterials can not only be used as tissue engineering scaffolds for skin regeneration, but also as drug carriers...
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The methylome and transcriptome of fetal skin: implications for scarless healing
PublicationAim: Fetal skin is known to heal without scarring. In mice, the phenomenon is observed until the 16–17 day of gestation – the day of transition from scarless to normal healing. The study aims to identify key methylome and transcriptome changes following the transition. Materials & methods: Methylome and transcriptome profiles were analyzed in murine dorsal skin using microarray approach. Results & conclusion: The genes associated...
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Use of optical skin phantoms for calibration of dermatological lasers
PublicationA wide range of dermatological diseases can be efficiently treated using laser heating. Nevertheless, before the new laser is introduced into clinical practice, its parameters and ability to interact with human skin have to be carefully examined. In order to do that optical skin phantoms can be used. Such phantoms closely imitate the scattering and absorption properties of real human skin tissue along with its thermal properties,...
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A device for measuring heat flux on a rocket skin surface
PublicationA novel method for measuring heat flux on a surface is presented. It is an extensive upgrade of currently known heat flux sensors used mostly in civil engineering. As the thermal environment of launchers, especially sounding rocket can have an enormous negative effect on payload, careful considerations have to be taken in the process of preparing insulation. Usually, thermal data provided by the launch vehicle manufacturer is limited...
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The effect of transglutaminase on the properties of salmon skin-gelatin films
PublicationCelem pracy była enzymatyczna modyfikacja folii otrzymanych z żelatyny rybnej. Źródłem żelatyny były surowe i wędzone skóry łososia. Stwierdzono, że czas żelowania roztworu żelatyny ulegał skróceniu w obecności transglutaminazy w badanym zakresie 0,1-0,2 mg/ml. Enzymatyczne modyfikacje prowadziły do obniżenia rozpuszczalności folii, jednakże w różnym stopniu zależnym od źródła białka. Obecność DTT lub cysteiny w mieszaninie reakcyjnej...
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Key Role of CRF in the Skin Stress Response System
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The role of interleukin 16 in the pathogenesis of selected skin diseases
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The effect of exposure to cold on dexterity and temperature of the skin and hands
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Impedance measurements of skin layered structure for burns determination.
PublicationW pracy analizowany jest dwuwarstwowy model skóry. Pokazano, że za pomocą wielokrotnych pomiarów immitancyjnych jest możliwe wyznaczenia zarówno parametrów elektrycznych oparzonej skóry jak i geometrycznych. Przedstawiono algorytm estymacji i procedurę pomiarową wyżej wymienionych parametrów.
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China Journal of Leprosy and Skin Diseases
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Thermal sequences database of the skin flaps in breast reconstruction and burns
PublicationThis paper presents a database of Active Dynamic Thermography (ADT) thermal sequences gathered throughout 6 year study on ADT application in skin flap blood perfusion monitoring and burn wounds diagnosis. For skin flap monitoring the database comprises of data collected during three different breast reconstruction procedures. The patients were monitored pre, intra and post surgically within 90 days period. The sequences were used...
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Thermal sequences database of the skin flaps in breast reconstruction and burns
PublicationThis paper presents a database of Active Dynamic Thermography (ADT) thermal sequences gathered throughout 6 year study on ADT application in skin flap blood perfusion monitoring and burn wounds diagnosis. For skin flap monitoring the database comprises of data collected during three different breast reconstruction procedures. The patients were monitored pre, intra and post surgically within 90 days period. The sequences were used...
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Self-Supervised Learning to Increase the Performance of Skin Lesion Classification
PublicationTo successfully train a deep neural network, a large amount of human-labeled data is required. Unfortunately, in many areas, collecting and labeling data is a difficult and tedious task. Several ways have been developed to mitigate the problem associated with the shortage of data, the most common of which is transfer learning. However, in many cases, the use of transfer learning as the only remedy is insufficient. In this study,...
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Numerical heat transfer model in skin burn depth simulations
PublicationW artykule przedstawiono numeryczny model wymiany ciepła zachodzącej w tkance skórnej . Wyniki symulacji na modelu zostały porównane z wynikami pomiarów In vivo na zwierzętach.