Search results for: chiral pharmaceuticals

• Pharmaceutical and forensic drug applications of chiral supercritical fluid chromatography

  Publication

  • J. Płotka-Wasylka
  • M. Biziuk
  • C. Morrison
  • J. Namieśnik

  - TRAC-TRENDS IN ANALYTICAL CHEMISTRY - Year 2014

  THE SUPERCRITICAL FLUID IS AN EXCELLENT CHOICE AS THE CHROMATOGRAPHIC MOBILE PHASE BECAUSE IT ALLOWS RAPID SEPARATION WITH HIGH EFFICIENCY AND APPLICATIONS INVOLVING ENANTIORESOLUTION ARE COMMON. SUPERCRITICAL FLUID CHROMATOGRAPHY (SFC) IS INCREASINGLY USED FOR ANALYTICAL, SEMI-PREPARATIVE AND PREPARATIVE PURIFICATION OF CHIRAL COMPOUNDS, INCLUDING PRODUCTION OF ENANTIOMERS THAT ARE MAINLY ENCOUNTERED DURING DRUG DEVELOPMENT. SFC...

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• Detection, identification and determination of chiral pharmaceutical residues in wastewater: Problems and challenges

  Publication

  • A. Dogan
  • J. Płotka-Wasylka
  • D. Kempińska-Kupczyk
  • J. Namieśnik
  • A. Kot-Wasik

  - TRAC-TRENDS IN ANALYTICAL CHEMISTRY - Year 2020

  Chiral pharmaceuticals (CPs) are widely used in different areas of human life, thus they are frequentlydetected in different ecosystems. However, before CPs reach the environment, wastewater is subjected todifferent treatment processes in order to remove them. Nevertheless, such processes may affect thechirality of CPs, thus it is very important to monitor CP levels during the wastewater treatment.This review addresses the present...

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