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Opinia o innowacyjności w odniesieniu do planowanego efektu prac badawczo – rozwojowych nad nowymi rodzajami profili ciężkich wraz z akcesoriami komplementarnymi
PublicationOpinia o innowacyjności w odniesieniu do planowanego efektu prac badawczo – rozwojowych nad nowymi rodzajami profili ciężkich wraz z akcesoriami komplementarnymi. Opinia związana z wystąpieniem o środki na dofinansowanie innowacyjnej technologii produkcji. Mocowania, pomosty, belki, konstrukcje skręcane.
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The Effect of Millisecond Pulsed Electric Fields (msPEF) on Intracellular Drug Transport with Negatively Charged Large Nanocarriers Made of Solid Lipid Nanoparticles (SLN): In Vitro Study
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The effect of high pressure and sub-zero temperature on total antioxidant capacity and the content of vitamin C, fatty acids and secondary products of lipid oxidation in human milk
PublicationThe objective of this study was to compare of the effects of high pressure of 193 MPa at - 20°C and Low Temperature Long Time pasteurization (LTLT or holder pasteurization, 62,5°C; 30 min) on the content and composition of fatty acids (FAs), concentrations of secondary products of lipid oxidation (TBARS), the total antioxidant capacity (TAC), total vitamin C and ascorbic acid (AsA) content in human milk. It was shown that no significant...
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Changes in the EPA and DHA content and lipids quality parameters of rainbow trout (Oncorhynchus mykiss, Walbaum) and carp (Cyprinus carpio, L.) at individual stages of hot smoking
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Protective impact of extract from Aronia melanocarpa berries against low-level exposure to cadmium-induced lipid peroxidation in the bone tissue: a study in a rat model
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A new dilution-enrichment sample preparation strategy for expanded metabolome monitoring of human breast milk that overcomes the simultaneous presence of low- and high-abundance lipid species
PublicationThe complex nature of human breast milk (HBM) makes samples difficult to analyze, requiring several extraction techniques and analytical platforms to obtain high metabolome coverage. In this work, we combined liquid-liquid extraction (LLE) and solid-phase extraction (SPE) techniques to prepare HBM samples to overcome the challenge of low- and high-abundance lipid species, enabling the semiquantitative analysis of total HBM lipids...
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The effect of exogenous application of methyl jasmonate on the lipid and carbohydrate content and composition of winter triticale (Triticosecale Wittm.) grain and the severity of fungal infections in triticale plants and grain
PublicationKernels of winter triticale (Triticosecale Wittm. cv. Dinaro) were analyzed. In the autumn of 2015, the effect of methyl jasmonate (MJ) on the germination of triticale kernels and the development of triticale seedlings was analyzed in a laboratory before kernels were sown in experimental plots. Kernels harvested from plots in August 2016 were analyzed to determine their lipid and carbohydrate content and composition and the severity...
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Wspomagana komputerowo weryfikacja określonego poziomu nienaruszalności bezpieczeństwa sil z wykorzystaniem autorskiej aplikacji ProSIL
PublicationW referacie przedstawiono oprogramowanie Pro SIL wspomagające zarządzanie bezpieczeństwem funkcjonalnym. Program ProSIL składa się z trzech modułów wspomagających: określanie wymaganego poziomu SIL (moduł ProSILen) weryfikację SIL (moduł ProSILer) oraz przeprowadzenie analizy warstw zabezpieczeń metodą LOPA. W aplikacji ProSIL zaimplementowano opracowaną w trakcie badań metodykę analizy bezpieczeństwa funkcjonalnego w projektowaniu...
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Proline, glutamic acid, and leucine rich protein 1 (PELP1) expression in deep paravertebral muscles in idiopathic scoliosis girls
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Selectivity Tuning by Natural Deep Eutectic Solvents (NADESs) for Extraction of Bioactive Compounds from Cytinus hypocistis—Studies of Antioxidative, Enzyme-Inhibitive Properties and LC-MS Profiles
PublicationIn the present study, the extracts of Cytinus hypocistis (L.) L using both traditional solvents (hexane, ethyl acetate, dichloromethane, ethanol, ethanol/water, and water) and natural deep eutectic solvents (NADESs) were investigated in terms of their total polyphenolic contents and antioxidant and enzyme-inhibitive properties. The extracts were found to possess total phenolic and total flavonoid contents in the ranges of 26.47–186.13...
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The Profile of Urinary Headspace Volatile Organic Compounds After 12-Week Intake of Oligofructose-Enriched Inulin by Children and Adolescents with Celiac Disease on a Gluten-Free Diet: Results of a Pilot, Randomized, Placebo-Controlled Clinical Trial
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Keratinocyte-derived small extracellular vesicles supply antigens for CD1a-resticted T cells and promote their type 2 bias in the context of filaggrin insufficiency
PublicationIntroduction: Exosome-enriched small extracellular vesicles (sEVs) are nanosized organelles known to participate in long distance communication between cells, including in the skin. Atopic dermatitis (AD) is a chronic inflammatory skin disease for which filaggrin (FLG) gene mutations are the strongest genetic risk factor. Filaggrin insufficiency affects multiple cellular function, but it is unclear if sEV-mediated cellular communication...
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Analysis of apolipoprotein A-IV expression and the levels of blood plasmamain lipid fractions of calves during the first week of life before and after theadministration of milk replacer supplemented with lactose
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The influence of plant protection by effective microorganisms on the content of bioactive phytochemicals in apples
PublicationThe phytochemicals of two apple cultivars (Yellow Transparent and Early Geneva) protected in two ways, conventionally with chemical pesticides or by effective microorganisms (EM), were compared. Two types of components were determined: lipids synthesised constitutively and generated via inducible pathways polyphenols along with antioxidant activity and profiles. The antioxidant activities assessed with ABTS, DPPH and Folin–Ciocalteu...
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Regulacja epigenetyczna a potencjał regeneracyjny ssaków. Badania globalnych profili metylacji w tkankach dorosłej myszy MRL/MpJ i w sercach noworodków myszy C57BL/6J.
PublicationW pracy tej otrzymano genomowe profile metylacji DNA dla dwóch modeli regeneracji u ssaków: (i) dorosłej myszy MRL/MpJ, która jest zdolna do zamykania otworów w małżowinie usznej oraz wykazuje podwyższone zdolności regeneracyjne w wielu innych narządach oraz (ii) sercach noworodków myszy, u których zachodzi regeneracja rozległych uszkodzeń lewej komory serca. Zidentyfikowano szereg odmiennie metylowanych regionów DNA, regionów DMR,...
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Enhanced expression of the proline synthesis gene P5CSA in relation to seed osmopriming improvement of Brassica napus germination under salinity stress
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Destructiveness of Profits and Outlays Associated with Operation of Offshore Wind Electric Power Plant. Part 1: Identification of a Model and its Components
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Association between plasma proteome profiles analysed by mass spectrometry, a lymphocyte-based DNA-break repair assay and radiotherapy-induced acute mucosal reaction in head and neck cancer patients
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Assessment of the Steering Precision of a Hydrographic Unmanned Surface Vessel (USV) along Sounding Profiles Using a Low-Cost Multi-Global Navigation Satellite System (GNSS) Receiver Supported Autopilot
Publicationhe performance of bathymetric measurements by traditional methods (using manned vessels) in ultra-shallow waters, i.e., lakes, rivers, and sea beaches with a depth of less than 1 m, is often difficult or, in many cases, impossible due to problems related to safe vessel maneuvering. For this reason, the use of shallow draft hydrographic Unmanned Surface Vessels (USV) appears to provide a promising alternative method for performing...
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The first Polish cohort of adult patients with common variable immunodeficiency from four specialized centers: do we provide standards of care?
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Expression of Estrogen Receptor Coactivator Proline-, Glutamic Acid- and Leucine-Rich Protein 1 within Paraspinal Muscles in Adolescents with Idiopathic Scoliosis
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Gas-phase quasi-degeneracy of zwitterionic and canonical tautomers of glycine and proline induced by the presence of the MAlF4(M = Li, Na, K) salts
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Qualitative analysis of phospholipids and their oxidised derivatives – used techniques and examples of their applications related to lipidomic research and food analysis
PublicationPhospholipids (PLs) are important biomolecules that not only constitute structural building blocks and scaffolds of cell and organelle membranes, but also play a vital role in cell biochemistry and physiology. Moreover, dietary exogenous PLs are characterized by high nutritional value and other beneficial health effects, which are confirmed by numerous epidemiological studies. For this reason, PLs are of high interest in lipidomics...
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Porównanie przebiegu enzymatycznej hydrolizy oleju rzepakowego i strukturyzowanych lipidów zawierających kwas behenowy. The comparision on the course of enzymatic hydrolysis of rapeseed oil and structured lipids containing behenoic acid.
PublicationPorównywano przebieg enzymatycznej hydrolizy oleju rzepakowego i strukturyzowanych lipidów zawierających kwas behenowy (C22:0). Hydroliza prowadzona była w obecności lipazy trzustkowej, w warunkach stymulujących proces trawienia. Stwierdzono, że olej rzepakowy hydrolizowany jest znacznie szybciej niż strukturyzowane lipidy z kwasem behenowym.
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Genetic Background and Antibiotic Resistance Profiles of K. pneumoniae NDM-1 Strains Isolated from UTI, ABU, and the GI Tract, from One Hospital in Poland, in Relation to Strains Nationally and Worldwide
PublicationIn recent years, there has been an observed increase in infections caused by carbapenem-resistant Klebsiella pneumonia (Kp) strains. The aim of this study was the phenotypic and genotypic analysis of eight K. pneumoniae NDM (Kp NDM) isolates, recovered in Poland during the years 2016 and 2018 from seven patients with urinary tract infections (UTIs), asymptomatic bacteriuria (ABU), or colonization of the gut. PCR melting profile...
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Efficient optimization approaches for microwave assisted extraction of high-quality antioxidant compounds from Salvia officinalis L.: UHPLC-HRMS differential analysis of phenolic profiles obtained by ultrasound and microwave extraction
PublicationThe study aims to optimize MAE of total phenolic compounds (TPC) and antioxidant capacity from Salvia officinalis L. leaves using a definitive screening design (DSD) and I-optimal design. UHPLC-HRMS analysis was used to identify and compare the composition of MAE and UAE optimal extracts. The results showed that DSD and I-optimal design were successfully applied for the optimization of MAE targeting phenolics and other antioxidants...
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Characteristics of Cucumis metuliferus, Actinidia deliciosa and Musa paradisica fragrance profiles using a comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection (GC×GC-TOF MS)
PublicationComprehensive two-dimensional gas chromatography with time-of-flight mass spectrometric detection (GC×GC-TOF-MS) is a modern analytical technique used in many fields. This technique enables an effective separation of volatile chemical compounds [1]. In recent years, the topic of healthy food and healthy living has become very popular. For this reason, more and more scientific publications related to the analysis of food products...
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The role of bile salts in digestion
PublicationBile salts (BS) are bio-surfactants present in the gastrointestinal tract (GIT) that play a crucial role in the digestion and absorption of nutrients. The importance of BS for controlled release and transport of lipid soluble nutrients and drugs has recently stimulated scientific interest in these physiological compounds. BS are so-called facial amphiphiles showing a molecular structure that is very distinct from classical surfactants....
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Two small RNAs conserved in Enterobacteriaceae provide intrinsic resistance to antibiotics targeting the cell wall biosynthesis enzyme glucosamine-6-phosphate synthase
PublicationFormation of glucosamine-6-phosphate GlcN6P) by enzyme GlcN6P synthase (GlmS) represents the first step in bacterial cell envelope synthesis. In Escherichia coli, expression of glmS is controlled by small RNAs (sRNAs) GlmY and GlmZ. GlmZ activates the glmS mRNA by base-pairing. When not required, GlmZ is bound by adapter protein RapZ and recruited to cleavage by RNase E inactivating the sRNA. The homologous sRNA GlmY activates...
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Designing a High-sensitivity Microscale Triple-band Biosensor based on Terahertz MTMs to provide a perfect absorber for Non-Melanoma Skin Cancer diagnostic
PublicationNon-melanoma skin cancer (NMSC) is among the most prevalent forms of cancer originating in the top layer of the skin, with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) being its primary categories. While both types are highly treatable, the success of treatment hinges on early diagnosis. Early-stage NMSC detection can be achieved through clinical examination, typically involving visual inspection. An alternative,...
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Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
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Load capacity of steel-aluminium brackets under static and cyclic laboratory tests
PublicationThe aim of the research is the laboratory investigation of steel-aluminium brackets employed to fasten lightweight curtain walls to building facilities. Static pressure, suction forces, and cyclic loads parallel to end plates (horizontal – to simulate wind influence) were applied in the study. The steel-aluminium brackets were tested on a reinforced concrete substrate made of C30/37 concrete class to simulate the real working conditions....
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Minichannel and minigap classification criteria based on the aspect ratio of the minigeometry: A numerical study
PublicationA detailed numerical investigation has been carried out to analyze the diabatic flow distribution and velocity profile in 18 minigeometries with various aspect ratios for V-type and I-type flow configurations (for 36 cases) assuming ethanol as a working fluid. The aim of the study is to distinguish the value of the aspect ratio for which the flow in minigeometry starts to be two-dimensional (minigap). Cases with a constant Reynolds...
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Correction: Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
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Problem of aggregation in dye-DNA interaction, calorimetry studies
PublicationNucleic acids are the biological target for many antimicrobial, antitumor and antiviral drugs. Ligand-DNA interactions can be classified into two major categories: 1. covalent binding, which can provide to intermolecular adducts, 2. physico-chemical interactions, which can be divided into intercalation (e.g. adriamycin) or groove binding (e.g. dystamycin). There are several methods to investigate interactions between drug and DNA....
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Studies on the treatment of lipid-rich wastewater and on the influence of soluble microbial products on activity of microorganisms.Studia nad obróbką ścieków bogatych w tłuszcze(lipidy) i oddziaływanie ubocznych produktów mikroorganizmów na ich aktywność.
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Designing a high-sensitivity dual-band nano-biosensor based on petahertz MTMs to provide a perfect absorber for early-stage non-melanoma skin cancer diagnostic
PublicationThe purpose of this study is development of a novel high-performance low-Petahertz (PHz) biosensor for non-melanoma skin cancer (NMSC) diagnosis. The presented device is designed to work within a microwave imaging regime, which is a promising alternative to conventional diagnostic methods such as visual examination, dermoscopy, and biopsy. The suggested biosensor incorporates a dual-band perfect absorber (operating bands at 0.909...
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Adipocyte Fatty Acid‐Binding Protein as a Novel Marker of Psoriasis and Clinical Response to Acitretin
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Serum Fatty Acid-Binding Protein 4 is Increased in Patients with Psoriasis
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Komputerowe wspomaganie procesu zarządzania bezpieczeństwem funkcjonalnym
PublicationW niniejszym rozdziale przedstawiono oprogramowanie ProSIL wspomagające zarządzanie bezpieczeństwem funkcjonalnym. Program ProSIL składa się z dwóch modułów wspomagających: określenie wymaganego poziomu SIL (moduł ProSILen) oraz weryfikację SIL (moduł ProSILer). W aplikacji ProSIL zaimplementowano opracowaną w trakcie badań metodykę analizy bezpieczeństwa funkcjonalnego w projektowaniu i użytkowaniu systemów SIS zgodnie z wymaganiami...
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Updating the Coupling Algorithm between HYDRUS and MODFLOW in the HYDRUS Package for MODFLOW
PublicationThe HYDRUS-based flow package for MODFLOW (the HPM or the HYDRUS package) is an existing unsaturated zone flow package for MODFLOW. In MODFLOW with the HPM, the groundwater modeling domain is discretized into regular grids that can be combined into multiple zones based on similarities in soil hydrology, topographical characteristics, and the depth to the groundwater. Each of these zones is assigned one unsaturated soil profile...
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Differences in Expression of Genes Involved in Bone Development and Morphogenesis in the Walls of Internal Thoracic Artery and Saphenous Vein Conduits May Provide Markers Useful for Evaluation Graft Patency
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Application of Barkhausen method to determine internal stresses in cold-rolled and hot-rolled sheets
PublicationThe paper presents investigations on internal stress distribution in plane hot—or cold-rolled sheets dedicated for the cold-formed profiles. The motivation of the research is a new profile design whose bending technology, incorporating a longitudinal welded joint and hot-dip galvanization after bending and welding introduces additional internal stresses. In order to identify the entirety of stresses in the process of sheet production...
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Phospholipids as potential prevention factor in carcinogenesis
PublicationPhospholipids are a group of complex lipids, which can be used in cancer chemoprevention. Glicerophospholipids are composed of fatty acids esterified to a glycerol backbone, a phosphate group and a hydrophilic residue such as: cho- line, ethanoloamine, serine or inositol. In the sn-2 position of glicerophospholipid usually there are unsaturated fatty acids, i.e. linolenic acid, while in the sn-1 position more typi- cal are saturated...
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Impact Assessment of Electric Vehicles Integration and Optimal Charging Schemes Under Uncertainty: A Case Study of Qatar
PublicationThe integration of electric vehicles (EVs) is rapidly growing compared to conventional vehicles in Qatar. To assess how these electric vehicles will impact Qatar’s distribution network, it is necessary to accurately model EV loads. However, EV loads exhibit uncertainties due to driving behaviour in charging time, state of charge (SOC), number of trips, and distance travelled. This necessitates the development of a probabilistic...
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Wavelet transform-based approach to defect identification in railway carbon contact strips.
PublicationPantographs of electric rail vehicles are fitted with carbon contact strips, which slide along the contact wire of catenary to provide constant electrical contact. Contact strips are exposed to wear and damages. Using damaged contact strips significantly increases the risk of catenary rupture. Therefore, their technical condition has to be inspected frequently. In previous work a 3D laser scanning system was proposed for recording...
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The role of non-profit open access journals in building the country's scientific potential: Reflections on ten years of the International Journal of Pedagogy, Innovation and New Technologies experience
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Budowa niskokalorycznych strukturyzowanych lipidów otrzymanych na drodze enzymatycznego przeestryfikowania oleju rzepakowego i oleiny palmowej kwasem behenowym. The structure of low-calorie structured lipids obtained by enzymatic interestrification of rapeseed oil and palm oil with behenoic acid.
PublicationNiskokaloryczne strukturyzowane lipidy otrzymano na drodze wbudowywania kwasu behenowego, charakteryzującego się niską strawnością, w pozycje sn-1,3 triacylogliceroli dwóch rodzajów oleju rzepakowego oraz oleiny polmowej. Reakcje acydolizy przeprowadzono w obecności biokatalizatora Lipozyme RM IM przez 3 godziny w temp. 72st.C. Otrzymane produkty po usunięciu wolnych kwasów tłuszczowych rozdzielono w kolumnie chromatograficznej...
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Chemistry of human breast milk – a comprehensive review of the composition and role of milk metabolites in child development
PublicationEarly nutrition has an enormous influence on a child's physiological function, immune system maturation and cognitive development. Human breast milk (HBM) is recognized as the gold standard for human infant nutrition. Accordingly to WHO report breastfeeding is consider as an unequalled way of providing ideal food to the infant, which is required for his healthy growth and development. HBM contains various macronutrients (carbohydrates,...
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Practical Eco-Driving Strategy for Suburban Electric Multiple Unit
PublicationIn this paper, a practical approach to velocity profile optimization for electric multiple unit was presented. The study focuses on a case of fast urban railway, which is a popular mean of transport across Tricity, Poland. Based on observations and measurements, a potential for improvement of energy efficiency by modifying the speed profile was recognized. In order to conduct necessary calculations, simulation model of railway...