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Search results for: ovarian cancer
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Revisiones en Cancer
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ANTI-CANCER DRUGS
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Cancer Drug Resistance
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Annals of Pancreatic Cancer
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MOLECULAR CANCER THERAPEUTICS
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PEDIATRIC BLOOD & CANCER
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SEMINARS IN CANCER BIOLOGY
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SUPPORTIVE CARE IN CANCER
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An optimized controlled rate slow cooling protocol for bovine ovarian tissue cryopreservation by means of X-ray computed tomography
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Personalized prediction of the secondary oocytes number after ovarian stimulation: A machine learning model based on clinical and genetic data
PublicationControlled ovarian stimulation is tailored to the patient based on clinical parameters but estimating the number of retrieved metaphase II (MII) oocytes is a challenge. Here, we have developed a model that takes advantage of the patient’s genetic and clinical characteristics simultaneously for predicting the stimulation outcome. Sequence variants in reproduction-related genes identified by next-generation sequencing were matched...
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Circadian Gene Polymorphisms Associated with Breast Cancer Susceptibility
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Towards Cancer Patients Classification Using Liquid Biopsy
PublicationLiquid biopsy is a useful, minimally invasive diagnostic and monitoring tool for cancer disease. Yet, developing accurate methods, given the potentially large number of input features, and usually small datasets size remains very challenging. Recently, a novel feature parameterization based on the RNA-sequenced platelet data which uses the biological knowledge from the Kyoto Encyclopedia of Genes and Genomes, combined with a classifier...
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Single nucleotide polymorphisms associated with papillary thyroid cancer
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Gene copy numbers of HER family in breast cancer
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Probiotic Bacteria: A Promising Tool in Cancer Prevention and Therapy
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Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface
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Coping strategies and sexual satisfaction in bladder cancer males
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Cancer immune escape: the role of antigen presentation machinery
PublicationThe mechanisms of antigen processing and presentation play a crucial role in the recognition and targeting of cancer cells by the immune system. Cancer cells can evade the immune system by downregulating or losing the expression of the proteins recognized by the immune cells as antigens, creating an immunosuppressive microenvironment, and altering their ability to process and present antigens. This review focuses on the mechanisms...
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Cancer-selective, single agent chemoradiosensitising gold nanoparticles
PublicationTwo nanometre gold nanoparticles (AuNPs), bearing sugar moieties and/or thiol-polyethylene glycol-amine (PEG-amine), were synthesised and evaluated for their in vitro toxicity and ability to radiosensitise cells with 220 kV and 6 MV X-rays, using four cell lines representing normal and cancerous skin and breast tissues. Acute 3 h exposure of cells to AuNPs, bearing PEG-amine only or a 50:50 ratio of alpha-galactose derivative and...
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The Effects of Single Nucleotide Polymorphisms in Cancer RNAi Therapies
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Inhibitors of angiogenesis in cancer therapy – synthesis and biological activity
PublicationAngiogenesis is the process of formation of new capillaries from preexisting blood vessels. Angiogenesis is involved in normal physiological processes, and plays an important role in tumor invasion and development of metastases. Vascular endothelial growth factor (VEGF) plays a key role in angiogenesis. VEGF is a mitogen for vascular endothelial cells and stimulates their proliferation. By inhibiting the biological activity of...
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Novel Inhibitor-Based Therapies for Thyroid Cancer—An Update
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Role of the Synergistic Interactions of Environmental Pollutants in the Development of Cancer
PublicationThere is a growing awareness that the large number of environmental pollutants we are exposed to on a daily basis are causing major health problems. Compared to traditional studies that focus on individual pollutants, there are relatively few studies on how pollutants mixtures interact. Several studies have reported a relationship between environmental pollutants and the development of cancer, even when pollutant levels are below...
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Neural network breast cancer relapse time prognosis
PublicationPrzedstawiono architekturę i wyniki testowania sztucznej sieci neuronowej w prognozowaniu czasu nawrotu choroby u kobiet chorych na raka piersi. Sieć neuronowa uczona była na danych zgromadzonych przez 20 lat. Dane opisują grupę 439 pacjentów za pomocą 40 parametrów. Spośród tych parametrów wybrano 6 najistotniejszych: liczbę przerzutowych węzłów chłonnych, wielkość guza, wiek, skalę według Blooma oraz stan receptorów estrogenowych...
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Darboux covariant equations of von Neumann type and their generalization.
PublicationOpisano nową klasę uogólnionych równań von Neumanna całkowalnych przez transformację Darboux. Uogólnienie zawiera jako przypadki szczególne nieliniowe równanie von Neumanna, r. Nahma, kratę Tody i inne.
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VARIANT DESIGNING IN the PRELIMINARY SMALL SHIP DESIGN PROCESS
PublicationShip designing is a complex process, as the ship itself is a complex, technical multi-level object which operates in the air/water boundary environment and is exposed to the action of many different external and internal factors resulting from the adopted technical solutions, type of operation, and environmental conditions. A traditional ship design process consists of a series of subsequent multistage iterations, which gradually...
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The Four-Feature Prognostic Models for Cancer-Specific and Overall Survival after Surgery for Localized Clear Cell Renal Cancer: Is There a Place for Inflammatory Markers?
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Cancer stem cells in drug resistance and drug screening: can we exploit the cancer stem cell paradigm in search for new antitumor agents?
PublicationPraca przedstawia przegląd literatury dotyczącej hipotezy komórek pierwotnych nowotworu, w szczególności w ich oporności na istniejące terapie. Dyskutowane jest także zagadnienie możliwości wykorzystania wiedzy o tych komórkach do konstrukcji nowych testów do badań przesiewowych in vitro w celu poszukiwania nowych leków przeciwnowotworowych.
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Development and validation of a model that includes two ultrasound parameters and the plasma D-dimer level for predicting malignancy in adnexal masses: an observational study
PublicationBackground: Pre-operative discrimination of malignant from benign adnexal masses is crucial for planning additional imaging, preparation, surgery and postoperative care. This study aimed to define key ultrasound and clinical variables and develop a predictive model for calculating preoperative ovarian tumor malignancy risk in a gynecologic oncology referral center. We compared our model to a subjective ultrasound assessment (SUA)...
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The associations between serum VEGF, bFGF and endoglin levels with microvessel density and expression of proangiogenic factors in malignant and benign ovarian tumors
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Muscle Cell Morphogenesis, Structure, Development and Differentiation Processes Are Significantly Regulated during Human Ovarian Granulosa Cells In Vitro Cultivation
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Can We Go beyond Pathology? The Prognostic Role of Risk Scoring Tools for Cancer-Specific Survival of Patients with Bladder Cancer Undergoing Radical Cystectomy
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Folate/homocysteine metabolism and lung cancer risk among smokers
PublicationBackground: Folate and homocysteine are involved in DNA synthesis and methylation processes, which are deregulated during carcinogenesis. Objectives: The aim of this study was to assess the relationship between folate/homocysteine concentrations, the functional polymorphisms of folate/homocysteine genes and lung cancer risk among cigarette smokers. Study design: The study included 132 lung cancer patients and 396 controls from...
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A deletion in CHEK2 of 5,395 bp predisposes to breast cancer in Poland
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XPD Common Variants and their Association with Melanoma and Breast Cancer Risk
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Common variants of xeroderma pigmentosum genes and prostate cancer risk
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An inherited NBN mutation is associated with poor prognosis prostate cancer
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Cancer Familial Aggregation (CFA) and G446A polymorphism in ARLTS1 gene
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The presence of prostate cancer at biopsy is predicted by a number of genetic variants
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Serum mass profile signature as a biomarker of early lung cancer
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Sulforaphane inhibits growth of phenotypically different breast cancer cells
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(CA)n Microsatellite polymorphism of ERBB-1 in breast cancer
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Biological Effects of Cold Atmospheric Pressure Plasma on Skin Cancer
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The p53-mediated cytotoxicity of photodynamic therapy of cancer: Recent advances
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Cytochromes P450 and Skin Cancer: Role of Local Endocrine Pathways
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Clinical Relevance of Circulating Tumor Cells in Prostate Cancer Management
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C-reactive Protein as a Diagnostic and Prognostic Factor of Endometrial Cancer
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The effects of RNA editing in cancer tissue at different stages in carcinogenesis
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Bladder cancer detection using a peptide substrate of the 20S proteasome
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Extracellular miRNAs as Biomarkers of Head and Neck Cancer Progression and Metastasis
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