Szymon Paczkowski - Publications - Bridge of Knowledge

Szymon Paczkowski

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Year 2021

Electrochemical simulation of metabolic reduction and conjugation reactions of unsymmetrical bisacridine antitumor agents, C-2028 and C-2053
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- JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS - Year 2021
Electrochemistry (EC) coupled with analysis techniques such as liquid chromatography (LC) and mass spectrometry (MS) has been developed as a powerful tool for drug metabolism simulation. The application of EC in metabolic studies is particularly favourable due to the low matrix contribution compared to in vitro or in vivo biological models. In this paper, the EC(/LC)/MS system was applied to simulate phase I metabolism of the representative...

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