Year -

• Compounds modulating function of telomeric proteins TRF1 and TRF2

  Projects

  Project manager: prof. dr hab. inż. Maciej Bagiński   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2023/49/B/NZ7/03456 agreement

• TopFUNG Yeast DNA topoisomerase II as a model molecular target for novel antifungal compounds

  Projects

  Project manager: dr hab. inż. Iwona Gabriel   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2022/45/B/NZ6/01149 agreement from 2023-07-03

• RADIUM Assessment of the influence of variable parameter conditions on obtaining the protein crystal of saccharopine dehydrogenase (NADP(+), L-glutamate-forming) from Candida albicans

  Projects

  Project manager: dr inż. Kamila Rząd

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to DEC-11/RADIUM/2023 agreement from 2023-07-12

• Antiviral potential and human cell-protective activity of bee bread derived from Polish apiaries.

  Projects

  Project manager: dr inż. Karolina Matejczuk   Financial Program Name: PRELUDIUM

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2022/45/N/NZ9/02710 agreement from 2023-01-09

• Anticancer activity of novel derivatives of 9,10-Anthraquinone Dithiocarbamates

  Projects

  Project manager: dr inż. Natalia Maciejewska   Financial Program Name: PRELUDIUM

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2021/41/N/NZ7/03707 agreement from 2021-11-26

• Biotechnological and pharmacological potential of bee products microbiota.

  Projects

  Project manager: dr hab. inż. Piotr Szweda   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2021/41/B/NZ9/03929 agreement from 2022-08-01

• Enzymes of the L-methionine biosynthetic pathway as novel molecular targets for antifungal chemotherapy

  Projects

  Project manager: dr hab. inż. Iwona Gabriel   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2020/39/B/NZ7/01519 agreement from 2021-07-08

• Assessment of the ability of application of folic acid and/or transferrin as a linkers between conjugates of quantum dots with unsymmetrical bisacridines to enhance their selectivity and cytotoxicity against lung and prostate cancer cells.

  Projects

  Project manager: dr inż. Joanna Pilch   Financial Program Name: PRELUDIUM

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2020/37/N/NZ7/01979 agreement from 2021-01-14

• ARGENTUM DNA topoisomerase inhibitors with acridine and acridone scaffold as a novel antifungal agents

  Projects

  Project manager: dr inż. Kamila Rząd

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to DEC-24/2020/IDUB/I.3.3 agreement from 2020-11-17

• Propolis and polyphenols derived from this product as potential antifungal agents

  Projects

  Project manager: dr hab. inż. Piotr Szweda   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2020/39/B/NZ7/02901 agreement from 2021-07-20

• Cleavable molecular nanocarrier:antimetabolite conjugates of antimicrobial activity

  Projects

  Project manager: prof. dr hab. inż. Sławomir Milewski   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2020/39/B/ST4/01509 agreement from 2021-06-08

• SUSDEV4REC Sustainable development of waste tires recycling by functionalization

  Projects

  Project manager: dr inż. Krzysztof Formela   Financial Program Name: Polsko-chiński Program Badawczy

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to WPC2/SUSDEV4REC/2021 agreement from 2021-06-15

• BisMolMechZM2020 Specific interactions of new antitumor unsymmetrical bisacridines, UAs, with DNA and ABC proteins and their potential to modulate the enzymatic activity and trancription of nuclear receptor as the elements of their molecular mechanism of action.

  Projects

  Project manager: prof. dr hab. inż. Zofia Mazerska   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2019/33/B/NZ7/02534 agreement from 2020-04-02

• Wstępna analiza potencjału przeciwgrzybowego pochodnych akrydyny i akrydonu

  Projects

  Project manager: dr inż. Kamila Rząd   Financial Program Name: MINIATURA

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to DEC-2019/03/X/NZ6/00895 agreement from 2019-12-04

• Badania oddziaływań pochodnych akrydyny oraz niesymetrycznych pochodnych bisakrydynowych z kwasami nukleinowymi metodami spektroskopii NMR

  Projects

  Project manager: dr hab. inż. Tomasz Laskowski   Financial Program Name: MINIATURA

  Project realized in Department of Pharmaceutical Technology and Biochemistry from 2017-10-03

• TARGETTELO New anticancer compounds interfering function of telomeres

  Projects

  Project manager: prof. dr hab. inż. Maciej Bagiński   Financial Program Name: STRATEGMED

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to STRATEGMED3/306853/9/NCBR/2017 agreement from 2017-05-17

• Biological response induced by high antitumor active unsymmetrical bisacridines against human colon and lung cancers and improved by nanoparticles drug delivery.

  Projects

  Project manager: dr hab. Ewa Augustin   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2016/23/B/NZ7/03324 agreement from 2017-10-02

• Derivatives of aromatic polyene macrolides of improved selective toxicity

  Projects

  Project manager: prof. dr hab. inż. Sławomir Milewski   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2016/23/B/NZ7/01223 agreement from 2017-07-04

• InterPhD II nie dotyczy

  Projects

  Project manager: prof. dr hab. inż. Maciej Bagiński   Financial Program Name: Program Operacyjny Wiedza Edukacja Rozwój

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to POWR.03.02.00-00-I002/16 agreement from 2017-09-25

• Aromatic aminotransferases from Candida albicans as molecular targets for antifungal chemotherapy.

  Projects

  Project manager: dr hab. inż. Iwona Gabriel   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2015/17/B/NZ6/04248 agreement from 2016-02-15

• SONATA BIS 5 Assess the potential of bee products and bacteriocins synthesized by the microflora of bee products as an alternative or complement to classical antibiotics

  Projects

  Project manager: dr hab. inż. Piotr Szweda   Financial Program Name: SONATA_BIS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2015/18/E/NZ6/00700 agreement from 2016-04-21

• Wpływ sfunkcjonalizowanych nanocząstek typu rdzeń-powłoka (Fe3O4@SiO2) na zahamowanie enzymów grzybiczych w systemach in vitro

  Projects

  Project manager: Ahmet Kertmen   Financial Program Name: PRELUDIUM

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2015/17/N/NZ7/01087 agreement from 2016-03-17

• Ne inhibitors of catalytic subunit of telomerase

  Projects

  Project manager: prof. dr hab. inż. Maciej Bagiński   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2014/13/B/NZ7/02207 agreement from 2015-01-28

• Semisynthetic analogs of a polyene macrolide antifungal antibiotic of improved selective toxicity

  Projects

  Project manager: prof. dr hab. inż. Maria Jolanta Milewska   Financial Program Name: OPUS

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2014/13/B/NZ7/02305 agreement from 2015-01-28

• Identyfikacja, oczyszczanie i badanie właściwości bakteriocyn o aktywności gronkowcobójczej

  Projects

  Project manager: Magdalena Zalewska   Financial Program Name: ETIUDA

  Project realized in Department of Pharmaceutical Technology and Biochemistry from 2014-09-08

• Rola kompleksów mTORC1 i mTORC2 w utrzymaniu fenotypu komórek macierzystych nowotworu podczas przejścia epitelialno-mezenchymalnego w modelu niedrobnokomórkowego raka płuc A549

  Projects

  Project manager: dr inż. Marcin Serocki   Financial Program Name: PRELUDIUM

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2013/11/N/NZ3/02022 agreement from 2014-08-21

• synth_md_cg Simulation of conformational changes related to the interdomain communication in the eukaryotic GlcN-6-P synthase by means of a large-scale molecular dynamics of the coarse-grained protein model

  Projects

  Project manager: Aleksandra Miszkiel   Financial Program Name: PRELUDIUM

  Project realized in Department of Pharmaceutical Technology and Biochemistry from 2014-03-14

• Studies on generation conditions and identification of reactive intermediates from model antitumor acridinone derivatives.

  Projects

  Project manager: dr hab. inż. Agnieszka Potęga   Financial Program Name: SONATA

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2012/07/D/NZ/03395 agreement from 2013-07-02

• One-pot synthesis of O-2-isocepham and N-2-isocepham derivatives bearing retroamide/tioretroamide or phosphono/thiophosphono function through the metal promoted cyclization – potential β-lactam antibiotics and β-lactamase inhibitors.

  Projects

  Project manager: prof. dr hab. inż. Janusz Rachoń   Financial Program Name: PRELUDIUM

  Project realized in Department of Pharmaceutical Technology and Biochemistry

• Analysis of population of bacteria belonging to genus Staphylococcus isolated from bovine mastitis towards production of bacteriocins

  Projects

  Project manager: Magdalena Zalewska   Financial Program Name: PRELUDIUM

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UMO-2012/07/N/NZ9/00939 agreement from 2016-09-09

• Inter PhD Inter PhD

  Projects

  Project manager: prof. dr hab. inż. Maciej Bagiński   Financial Program Name: Kapitał Ludzki

  Project realized in Department of Pharmaceutical Technology and Biochemistry according to UDA.POKL.04.01.01-00-368/09-00 agreement from 2009-12-31

• DRUGRES Novel potential antifungal drugs active against multidrug-resistant yeasts from the Candida genus

  Projects

  Project manager: prof. dr hab. inż. Sławomir Milewski   Financial Program Name: Polsko-indyjski konkurs na wymianę osobową

  Project realized in Department of Pharmaceutical Technology and Biochemistry

• Breast cancer - a new target for unsymmetrical bisacridine derivatives.

  Projects

  Project manager: dr inż. Monika Pawłowska   Financial Program Name: MINIATURA

  Project realized in Department of Pharmaceutical Technology and Biochemistry

• Development of an effective isolation method of amphotericin B analogues of potential clinical importance

  Projects

  Project manager: dr inż. Paweł Szczeblewski   Financial Program Name: MINIATURA

  Project realized in Department of Pharmaceutical Technology and Biochemistry