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Catalog Publications

Year 2023
  • On a 3D material modelling of smart nanocomposite structures
    Publication

    - INTERNATIONAL JOURNAL OF ENGINEERING SCIENCE - Year 2023

    Smart composites (SCs) are utilized in electro-mechanical systems such as actuators and energy harvesters. Typically, thin-walled components such as beams, plates, and shells are employed as structural elements to achieve the mechanical behavior desired in these composites. SCs exhibit various advanced properties, ranging from lower order phenomena like piezoelectricity and piezomagneticity, to higher order effects including flexoelectricity...

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  • On analysis of nanocomposite conical structures
    Publication

    - INTERNATIONAL JOURNAL OF ENGINEERING SCIENCE - Year 2023

    This research examines the analysis of rotating truncated conical baskets reinforced by carbon nanotubes around the two independent axes. A time-dependent analysis is considered, and the nonlinear dynamic governing equations are extracted using the energy method. Carbon nanotubes (CNTs) reinforced the conical basket, and the structure's mechanical properties are determined based on the several distributions of carbon nanotubes....

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  • On dynamic modeling of piezomagnetic/flexomagnetic microstructures based on Lord–Shulman thermoelastic model

    We study a time-dependent thermoelastic coupling within free vibrations of piezomagnetic (PM) microbeams considering the flexomagnetic (FM) phenomenon. The flexomagneticity relates to a magnetic field with a gradient of strains. Here, we use the generalized thermoelasticity theory of Lord–Shulman to analyze the interaction between elastic deformation and thermal conductivity. The uniform magnetic field is permeated in line with...

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  • On dynamics of origami-inspired rod
    Publication

    We discuss the dynamics of a relatively simple origami-inspired structure considering discrete and continuum models. The latter was derived as a certain limit of the discrete model. Here we analyze small in-plane deformations and related equations of infinitesimal motions. For both models, dispersion relations were derived and compared. The comparison of the dispersion relations showed that the continuum model can capture the behavior...

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  • On implementation of fibrous connective tissues’ damage in Abaqus software
    Publication

    Connective fibrous tissues, such as tendons and ligaments, in humans and animals exhibit hyperelastic behaviour. The constitution of the material of these tissues is anisotropic due to the presence of the collagen fibres, where one family of fibres is the typical case. Traumatic events and/or aging may sometimes lead to the damage of the tissue. The study of motion of affected joints or limbs is usually not permitted in vivo. This...

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  • On time-dependent nonlinear dynamic response of micro-elastic solids

    A new approach to the mechanical response of micro-mechanic problems is presented using the modified couple stress theory. This model captured micro-turns due to micro-particles' rotations which could be essential for microstructural materials and/or at small scales. In a micro media based on the small rotations, sub-particles can also turn except the whole domain rotation. However, this framework is competent for a static medium....

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  • Pharmacomicrobiomics of cell-cycle specific anti-cancer drugs – is it a new perspective for personalized treatment of cancer patients?
    Publication
    • K. Kaźmierczak-Siedlecka
    • N. Bulman
    • P. Ulasiński
    • B. K. Sobocki
    • K. Polom
    • L. Marano
    • L. Kalinowski
    • K. Skonieczna-Żydecka

    - Gut Microbes - Year 2023

    Intestinal bacteria are equipped with an enzyme apparatus that is involved in the active biotrans-formation of xenobiotics, including drugs. Pharmacomicrobiomics, a new area of pharmacology, analyses interactions between bacteria and xenobiotics. However, there is another side to the coin. Pharmacotherapeutic agents can significantly modify the microbiota, which consequently affects their efficacy. In this review, we comprehensively...

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  • Postbiotics in oncology: science or science fiction?
    Publication
    • A. Kudra
    • K. Kaźmierczak-Siedlecka
    • B. K. Sobocki
    • D. Muszyński
    • J. Polom
    • L. Carbone
    • L. Marano
    • F. Roviello
    • L. Kalinowski
    • E. Stachowska

    - Frontiers in Microbiology - Year 2023

    The gut microbiome has been increasingly understood to play a critical role in carcinogenesis and cancer disease progression. The most recent research advancements have shown that different tools of microbiota manipulation contribute to gut microbiome–immune–oncology axis modulation, offering exciting opportunities for targeted interventions aimed at improving the efficacy of established anti-cancer therapy. Postbiotics are a new...

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  • Protein overproduction alters exosome secretion in Chinese hamster ovary cells
    Publication
    • A. Steć
    • M. Targońska
    • E. Karkosińska
    • M. Słowik
    • A. Płoska
    • L. Kalinowski
    • B. Wielgomas
    • K. Waleron
    • J. Jasiecki
    • S. Dziomba

    - ANALYTICAL AND BIOANALYTICAL CHEMISTRY - Year 2023

    Despite the abundance of available cell lines, nearly 70% of all recombinant therapeutic proteins today are produced in Chi-nese hamster ovary (CHO) cells. The impact of protein overproduction on the secretion of exosomes by CHO cells has been investigated here. Increased secretion of extracellular vesicles (EVs) by protein overexpressing CHO cells was demonstrated with protein content assay, nanoparticle tracking analysis, and...

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  • Proteomic and Metabolomic Changes in Psoriasis Preclinical and Clinical Aspects
    Publication
    • A. Radulska
    • I. Pelikant-Malecka
    • K. Jendernalik
    • I. T. Dobrucki
    • L. Kalinowski

    - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2023

    Skin diseases such as psoriasis (Ps) and psoriatic arthritis (PsA) are immune-mediated inflammatory diseases. Overlap of autoinflammatory and autoimmune conditions hinders diagnoses and identifying personalized patient treatments due to different psoriasis subtypes and the lack of verified biomarkers. Recently, proteomics and metabolomics have been intensively investigated in a broad range of skin diseases with the main purpose...

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  • Proximal fibular osteotomy as a treatment for degenerative meniscal extrusion
    Publication

    - MEDICAL HYPOTHESES - Year 2023

    Meniscal extrusion treatment is a key focus area for research and clinical study of degenerative knee pathology. The contact forces between the meniscus and the bones cause external displacements of the meniscus that are resisted by the circumferential fibres. The main risk factors for the excessive deformation of the meniscus are meniscal root tears, disruption of the circumferential fibres, knee malalignment and high body mass...

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  • Przegląd aplikacji zużytych łopat turbin wiatrowych na potrzeby budownictwa infrastrukturalnego

    Artykuł zawiera przedstawienie aktualnego stanu wiedzy na temat recyklingu i ponownego użycia łopat wirników turbin wiatrowych na potrzeby budownictwa infrastrukturalnego. Poruszana problematyka stała się w ostatnim czasie bardzo istotna, a prognozy i statystyki pokazują, że najbliższe lata, będące jednocześnie okresem intensywnego rozwoju energetyki wiatrowej, będą jeszcze bardziej niż kiedykolwiek wymagały opracowania metody...

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  • RAGE as a Novel Biomarker for Prostate Cancer: A Systematic Review and Meta-Analysis
    Publication
    • C. C. Applegate
    • M. B. Nelappana
    • E. A. Nielsen
    • L. Kalinowski
    • I. T. Dobrucki
    • L. W. Dobrucki

    - Cancers - Year 2023

    The receptor for advanced glycation end-products (RAGE) has been implicated in driving prostate cancer (PCa) growth, aggression, and metastasis through the fueling of chronic inflammation in the tumor microenvironment. This systematic review and meta-analysis summarizes and analyzes the current clinical and preclinical data to provide insight into the relationships among RAGE levels and PCa, cancer grade, and molecular effects....

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  • Speed estimation of a car at impact with a W-beam guardrail using numerical simulations and machine learning

    This paper aimed at developing a new method of estimating the impact speed of a passenger car at the moment of a crash into a W-beam road safety barrier. The determination of such a speed based on the accident outcomes is demanding, because often there is no access to full accident data. However, accurate determination of the impact speed is one of the key elements in the reconstruction of road accidents. A machine learning algorithm...

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  • Sustainable utilization of copper post-flotation waste in cement composites

    The current way of managing the copper ore flotation waste is by placing it in waste neutralization facilities. However, flotation waste has great potential in application in cement composites. The article presents the detailed characteristics of post-flotation waste (PFW) and three types of cements: CEM I, CEM II/B-V, and CEM III/A, 42.5 MPa class. The post-flotation waste added for 20% of the cement mass increase the water demand...

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  • Technique for reducing erosion in large-scale circulating fluidized bed units
    Publication

    - POWDER TECHNOLOGY - Year 2023

    This paper presents a methodology, implemented for a real industrial-scale circulating fluidized bed boiler, to mitigate the risk of heating surfaces exposed to an intensive particle erosion process. For this purpose, a machine learning algorithm was developed to support the boiler reliability management process. Having a tool that can help mitigate the risk of uncontrolled power unit failure without expensive and technically complex...

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  • Textile reinforced concrete members subjected to tension, bending, and in-plane loads: Experimental study and numerical analyses
    Publication

    - CONSTRUCTION AND BUILDING MATERIALS - Year 2023

    Textile reinforced concrete has raised increasing research interest during the last years, mainly due to its potential to be used for freeform shell structures involving complex load situations. Yet, most experimental work has focused on test setups with primarily uniaxial loading. In the current work, such setups are complemented with a novel test setup of deep beams, including in-plane bending and shear. Further, nonlinear finite...

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  • The Unfolded Protein Response: A Double-Edged Sword for Brain Health
    Publication
    • M. Gebert
    • J. Sławski
    • L. Kalinowski
    • J. F. Collawn
    • R. Bartoszewski

    - Antioxidants - Year 2023

    Efficient brain function requires as much as 20% of the total oxygen intake to support normal neuronal cell function. This level of oxygen usage, however, leads to the generation of free radicals, and thus can lead to oxidative stress and potentially to age-related cognitive decay and even neurodegenerative diseases. The regulation of this system requires a complex monitoring network to maintain proper oxygen homeostasis. Furthermore,...

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  • Thermomagnetic behavior of a semiconductor material heated by pulsed excitation based on the fourth-order MGT photothermal model
    Publication

    - CONTINUUM MECHANICS AND THERMODYNAMICS - Year 2023

    This article proposes a photothermal model to reveal the thermo-magneto-mechanical properties of semiconductor materials, including coupled diffusion equations for thermal conductivity, elasticity, and excess carrier density. The proposed model is developed to account for the optical heating that occurs through the semiconductor medium. The Moore–Gibson–Thompson (MGT) equation of the fourth-order serves as the theoretical framework...

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Year 2022