prof. dr hab. inż. Jacek Czub
Zatrudnienie
- Profesor w Katedra Chemii Fizycznej
- Kierownik katedry w Katedra Chemii Fizycznej
Media społecznościowe
Kontakt
- jacczub@pg.edu.pl
Profesor
- Miejsce pracy
- Budynek A Wydziału Chemicznego pokój 219
- Telefon
- (58) 347 20 92
Kierownik katedry
- Miejsce pracy
- Budynek A Wydziału Chemicznego pokój 212
- Telefon
- (58) 347 16 10
Wybrane publikacje
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Localization and Orientation of Xanthophylls in a Lipid Bilayer
Xanthophylls (polar carotenoids) play diverse biological roles, among which are modulation of the physical properties of lipid membranes and protection of biomembranes against oxidative damage. Molecular mechanisms underlying these functions are intimately related to the localization and orientation of xanthophyll molecules in lipid membranes. In the present work, we address the problem of localization and orientation of two xanthophylls...
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Self-Association of Amphotericin B: Spontaneous Formation of Molecular Structures Responsible for the Toxic Side Effects of the Antibiotic
Amphotericin B (AmB) is a lifesaving antibiotic used to treat deep-seated mycotic infections. Both the pharmaceutical activity and highly toxic side effects of the drug rely on its interaction with biomembranes, which is governed by the molecular organization of AmB. In the present work we present detailed analysis of self-assembly of AmB molecules in different environments, interesting from the physiological standpoint, based...
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Keep It Flexible: Driving Macromolecular Rotary Motions in Atomistic Simulations with GROMACS
We describe a versatile method to enforce the rotation of subsets of atoms, e.g., a protein subunit, in molecular dynamics (MD) simulations. In particular, we introduce a “flexible axis” technique that allows realistic flexible adaptions of both the rotary subunit as well as the local rotation axis during the simulation. A variety of useful rotation potentials were implemented for the GROMACS 4.5 MD package. Application to the...
Uzyskane stopnie/tytuły naukowe
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2008-07-15
Nadanie stopnia naukowego
dr inż. Biotechnologia - nauki chemiczne (Dziedzina nauk chemicznych)
wyświetlono 7595 razy