Unresectable malignant obstructive jaundice: a 2-year experience of EUS-guided biliary drainage - Publikacja - MOST Wiedzy

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Unresectable malignant obstructive jaundice: a 2-year experience of EUS-guided biliary drainage

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Objectives: Endoscopic biliary drainage is a first-line treatment in patients with unresectable malignant biliary obstruction. In most cases the drainage is conducted using endoscopic retrograde cholangiopancreatography (ERCP). Percutaneous transhepatic biliary drainage or endosonography-guided biliary drainage (EUS-BD) represents therapeutic options after unsuccessful ERCP. Here we report on 2 years experience in the management of patients diagnosed with malignant biliary obstruction using EUS-BD. Methods: Retrospective data were collected on patients who underwent EUS-BD due to malignant biliary obstruction at our centre between April 2016 and April 2018. Only patients who had two unsuccessful attempts of ERCP prior to EUS-BD were included. We analysed the technical success (ie, creation of anastomosis and successful placement of a stent) and complication rate of EUS-BD, and monitored changes in serum bilirubin and liver function tests after 2 days, and at least 2 weeks, following the procedure. Results: Screening of 1781 ERCP procedures performed in our department during the inclusion period led to the identification of 31 patients (18 women, age range 51–92 years, 58% with pancreatic cancer) who fulfilled the inclusion criteria. Hepaticogastrostomy and choledochoduodenostomy were performed in 12 and 19 patients, respectively. The technical success rate was 97% and the complication rate was 12.9%. EUS-BD resulted in a significant decrease in serum bilirubin (p<0.01). Conclusions: EUS-BD represents a reasonable therapeutic option after unsuccessful ERCP in patients with malignant biliary obstruction. Possible complications have to be kept in mind and this procedure should be performed at centres experienced in ERCP and EUS.

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Kategoria:
Publikacja w czasopiśmie
Typ:
artykuły w czasopismach
Opublikowano w:
BMJ Supportive & Palliative Care nr 14, strony e1704 - e1707,
ISSN: 2045-435X
Język:
angielski
Rok wydania:
2024
Opis bibliograficzny:
Staroń R., Rzucidło M., Macierzanka A., Krawczyk M., Gutkowski K., Krupa Ł.: Unresectable malignant obstructive jaundice: a 2-year experience of EUS-guided biliary drainage// BMJ Supportive & Palliative Care -Vol. 14,iss. e2 (2024), s.e1704-e1707
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1136/bmjspcare-2020-002335
Źródła finansowania:
  • Publikacja bezkosztowa
Weryfikacja:
Politechnika Gdańska

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