- Nauki farmaceutyczne (Dziedzina nauk medycznych i nauk o zdrowiu)
- Nauki medyczne (Dziedzina nauk medycznych i nauk o zdrowiu)
- Nauki o zdrowiu (Dziedzina nauk medycznych i nauk o zdrowiu)
- Technologia żywności i żywienia (Dziedzina nauk rolniczych)
- Weterynaria (Dziedzina nauk rolniczych)
- Nauki chemiczne (Dziedzina nauk ścisłych i przyrodniczych)
Punkty Ministerialne: Pomoc
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Prace opublikowane w tym czasopiśmie
Lipoic Acid-Coated Silver Nanoparticles: Biosafety Potential on the Vascular Microenvironment and Antibacterial PropertiesPublikacja
Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy MetabolismPublikacja
In spite of the current advances and achievements in cancer treatments, colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in both men and women worldwide. Drug resistance, adverse side effects and high rate of angiogenesis, metastasis and tumor relapse remain one of the greatest challenges in long-term management of CRC and urges need for new leads of anticancer drugs. We demonstrate that CRC...
Consequences of New Approach of Chemical Stability Tests of Active Pharmaceutical Ingredients (APIs)Publikacja
There is a great need of broaden look on stability tests of active pharmaceuticalingredients (APIs) in comparison with current requirements contained in pharmacopeia.By usage of many modern analytical methods the conception of monitoring the changesof APIs during initial stage of their exposure to harmful factors has been developed. Newknowledge must be acquired in terms of identification of each degradation...
Direct human contact with siloxanes (silicones): safety or risk. Part 1: characteristics of siloxanes (siliconesPublikacja
Siloxanes are commonly known as silicones. They belong to the organosiliconcompounds and are exclusively obtained by synthesis. Their chemical structuredetermines a range of physicochemical properties which were recognized as unique.Due to the susceptibility to chemical modifications, ability to create short, long orcomplex polymer particles, siloxanes found an application in many areas of human life.
Forced degradation studies of ivabradine and in silico toxicology predictions for its new designated impuritiesPublikacja
All activities should aim to eliminate genotoxic impurities and/or protect the API againstdegradation. There is a necessity to monitor impurities from all classification groups,hence ivabradine forced degradation studies were performed. Ivabradine was provedto be quite durable active substance, but still new and with insufficient stability data.Increased temperature, acid, base, oxidation reagents and...
Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated ImpuritiesPublikacja
All activities should aim to eliminate genotoxic impurities and/or protect the API against degradation. There is a necessity to monitor impurities from all classification groups, hence ivabradine forced degradation studies were performed. Ivabradine was proved to be quite durable active substance, but still new and with insufficient stability data. Increased temperature, acid, base, oxidation reagents and light were found to cause...
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