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- inżynieria środowiska, górnictwo i energetyka (Dziedzina nauk inżynieryjno-technicznych)
- biologia medyczna (Dziedzina nauk medycznych i nauk o zdrowiu)
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Punkty Ministerialne: Pomoc
| Rok | Punkty | Lista |
|---|---|---|
| Rok 2024 | 40 | Ministerialna lista czasopism punktowanych 2024 |
| Rok | Punkty | Lista |
|---|---|---|
| 2024 | 40 | Ministerialna lista czasopism punktowanych 2024 |
| 2023 | 40 | Lista ministerialna czasopism punktowanych 2023 |
| 2022 | 40 | Lista ministerialna czasopism punktowanych (2019-2022) |
| 2021 | 40 | Lista ministerialna czasopism punktowanych (2019-2022) |
| 2020 | 40 | Lista ministerialna czasopism punktowanych (2019-2022) |
| 2019 | 40 | Lista ministerialna czasopism punktowanych (2019-2022) |
| 2018 | 20 | A |
| 2017 | 20 | A |
| 2016 | 20 | A |
| 2015 | 20 | A |
| 2014 | 20 | A |
| 2013 | 20 | A |
| 2012 | 20 | A |
| 2011 | 20 | A |
| 2010 | 27 | A |
Model czasopisma:
Punkty CiteScore:
| Rok | Punkty |
|---|---|
| Rok 2023 | 3.2 |
| Rok | Punkty |
|---|---|
| 2023 | 3.2 |
| 2022 | 3.1 |
| 2021 | 2.6 |
| 2020 | 2.4 |
| 2019 | 2.1 |
| 2018 | 2 |
| 2017 | 2.1 |
| 2016 | 2 |
| 2015 | 1.8 |
| 2014 | 1.7 |
| 2013 | 1.7 |
| 2012 | 1.6 |
| 2011 | 1.4 |
Impact Factor:
Sherpa Romeo:
Prace opublikowane w tym czasopiśmie
Filtry
wszystkich: 4
Katalog Czasopism
Rok 2019
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New potent STS inhibitors based on fluorinated 4-(1-phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamates
PublikacjaA series of fluorinated analogs based on the frameworks of 4-(1- phenyl-1H-[1,2,3]triazol-4-yl)-phenyl sulfamates have been synthesized as steroid sulfatase (STS) inhibitors. The design of chemical structures of new potential STS inhibitors was supported by molecular docking techniques to identify potential interactions between inhibitors and amino acid residues located in the STS active site. The STS inhibitory potency was evaluated...
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Synthesis and antiproliferative activity of new mycophenolic acid conjugates with adenosine derivatives
PublikacjaNew conjugates of mycophenolic acid (MPA) and adenosine derivatives were synthesized and assessed as potential immunosuppressants on Jurkat cell line and peripheral blood mononuclear cells (PBMC) from healthy donors. As compared to MPA, all compounds were found to be more active against Jurkat cell line. The antiproliferative activities were compared with MPA and adenosine, in both 2′,3′-O-isopropylidene protected and free hydroxyl...
Rok 2016
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New conjugates of mycophenolic acid and their antiproliferative activity
PublikacjaThe new conjugates of mycophenolic acid (MPA) were obtained in the reaction of N6-(ω-aminoalkyl)adenosines with MPA in the presence of EDCI as a coupling reagent. New compounds 4a–h were evaluated on leukemia cell line (Jurkat) and PBMC from healthy donors. Length of the linker influenced observed activity. The compound 4b possessing 1,3-diamine spacer exhibited the most promising results and can be considered to further investigations.
Rok 2015
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Synthesis and biological evaluation of thiophosphate tricyclic coumarin derivatives as steroid sulfatase inhibitors
PublikacjaSteroid sulfatase (STS) enzyme inhibition is an important approach to the management of hormone-dependent breast cancer. In this paper, we report convenient methods for the synthesis and biological evaluation of thiophosphate tricyclic coumarin analogs exhibiting STS activity. The described methods are based on the straightforward preparation of 7-hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-2-one, 3-hydroxy- 7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one,...
wyświetlono 719 razy