Rok 2024

• Evaluation of the Effectiveness of Compression Therapy Combined with Exercises Versus Exercises Only Among Lipedema Patients Using Various Outcome Measures

  Publikacja

  • M. Czerwińska
  • M. Gruszecki
  • J. Rumiński
  • R. Hansdorfer-Korzon

  - Life - Rok 2024

  The treatment of lipedema remains challenging, largely due to widespread misconceptions. Selecting the appropriate treatment method necessitates the use of accurate outcome measures. This study aims to evaluate the effectiveness of compression therapy combined with exercises versus exercises alone in lipedema patients using various outcome measures. Twenty-four women with lipedema were divided into two equal groups: one group received...

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Rok 2021

• Influence of Escherichia coli on Expression of Selected Human Drug Addiction Genes

  Publikacja

  • R. Kotlowski (dawniej: R. Kotłowski)

  - Life - Rok 2021

  The impact of enteric microflora on the expression of genes associated with cocaine and amphetamine addiction was described. Human genome-wide experiments on RNA transcripts expressed in response to three selected Escherichia coli strains allowed for significant alteration (p > 0.05) of the linear regression model between HT-29 RNA transcripts associated with the KEGG pathway:hsa05030:Cocaine addiction after 3 h stimulation with...

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Rok 2020

• Association of Genes Related to Oxidative Stress with the Extent of Coronary Atherosclerosis

  Publikacja

  • M. Racis
  • A. Stanisławska-Sachadyn
  • W. Sobiczewski
  • M. Wirtwein
  • M. Krzemiński
  • N. Krawczyńska
  • J. Limon
  • A. Rynkiewicz
  • M. Gruchała

  - Life - Rok 2020

  Oxidative stress is believed to play a critical role in atherosclerosis initiation and progression. In line with this, in a group of 1099 subjects, we determined eight single nucleotide polymorphisms (SNPs) related to oxidative stress (PON1 c.575A>G, MPO c.463G>A, SOD2 c.47T>C, GCLM c.590C>T, NOS3 c.894G>T, NOS3 c.786T>C, CYBA c.214C>T, and CYBA c.932A>G) and assessed the extent of atherosclerosis in coronary arteries based on...

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• Higher Responsiveness to Rosuvastatin in Polygenic versus Monogenic Hypercholesterolemia: A Propensity Score Analysis

  Publikacja

  • A. Mickiewicz
  • M. Futema
  • A. Ćwiklinska
  • A. Kuchta
  • M. Jankowski
  • M. F. Kaszubowski (dawniej: M. Kaszubowski)
  • M. Chmara
  • B. Wasąg
  • M. Fijałkowski
  • M. Jaguszewski... i 2 innych

  - Life - Rok 2020

  Background: The monogenic defect in familial hypercholesterolemia (FH) is detected in ∼40% of cases. The majority of mutation-negative patients have a polygenic cause of high LDL-cholesterol (LDL-C). We sought to investigate whether the underlying monogenic or polygenic defect is associated with the response to rosuvastatin. Methods: FH Individuals were tested for mutations in LDLR and APOB genes. A previously established LDL-C-specific...

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