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Wybrane publikacje

  • Selected organophosphorus compounds with biological activity. Applications in medicine

    The purpose of this article is to provide an overview of the latest applications of organophosphorus compounds (OPs) that exhibit biological activity. A large family of OPs have become popular in recent years. The practical application of OPs in modern medicine has been attributed to their unique properties. In this article, the methods used to select these compounds will be emphasized. This paper will first outline the findings...

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  • Novel 1,2,4-Oxadiazole Derivatives in Drug Discovery

    Abstract: Five-membered 1,2,4-oxadiazole heterocyclic ring has received considerable attention because of its unique bioisosteric properties and an unusually wide spectrum of biological activities. Thus, it is a perfect framework for the novel drug development. After a century since the 1,2,4-oxadiazole have been discovered, the uncommon potential attracted medicinal chemists’ attention, leading to the discovery of a few presently...

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  • HDAC Inhibitors: Innovative Strategies for Their Design and Applications

    • M. Daśko
    • I. Ortín
    • A. Ramos

    - MOLECULES - Rok 2022

    Histone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are linked to the development of many types of cancer and neurodegenerative diseases, making them interesting molecular targets for the design of new efficient drugs...

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Uzyskane stopnie/tytuły naukowe

  • 2018-10-09

    Nadanie stopnia naukowego

    dr inż. Nauki chemiczne (Dziedzina nauk ścisłych i przyrodniczych)

wyświetlono 4688 razy