A review: Fabrication of porous polyurethane scaffolds - Publikacja - MOST Wiedzy


A review: Fabrication of porous polyurethane scaffolds


The aim of tissue engineering is the fabrication of three-dimensional scaffolds that can be used for the reconstruction and regeneration of damaged or deformed tissues and organs. A wide variety of techniques have been developed to create either fibrous or porous scaffolds from polymers, metals, composite materials and ceramics. However, the most promising materials are biodegradable polymers due to their comprehensive mechanical properties, ability to control the rate of degradation and similarities to natural tissue structures. Polyurethanes (PUs) are attractive candidates for scaffold fabrication, since they are biocompatible, and have excellent mechanica properties and mechanical flexibility. PU can be applied to various methods of porous scaffold fabrication, among which are solvent casting/particulate leaching, thermally induced phase separation, gas foaming, emulsion freeze-drying and melt moulding. Scaffold properties obtained by these techniques, including pore size, interconnectivity and total porosity, all depend on the thermal processing parameters, and the porogen agent and solvents used. In this review, various polyurethane systems for scaffolds are discussed, aswell as methods of fabrication, including the latest developments, and their advantages and disadvantages.


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Informacje szczegółowe

Publikacja w czasopiśmie
artykuł w czasopiśmie wyróżnionym w JCR
Opublikowano w:
Materials Science & Engineering C-Materials for Biological Applications nr 48, strony 586 - 591,
ISSN: 0928-4931
Rok wydania:
Opis bibliograficzny:
Janik H., Marzec M.: A review: Fabrication of porous polyurethane scaffolds// Materials Science & Engineering C-Materials for Biological Applications. -Vol. 48, (2015), s.586-591
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1016/j.msec.2014.12.037
Politechnika Gdańska

wyświetlono 27 razy

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