Ciprofloxacin-modified degradable hybrid polyurethane-polylactide porous scaffolds developed for potential use as an antibacterial scaffold for regeneration of skin - Publikacja - MOST Wiedzy

Wyszukiwarka

Ciprofloxacin-modified degradable hybrid polyurethane-polylactide porous scaffolds developed for potential use as an antibacterial scaffold for regeneration of skin

Abstrakt

The aim of the performed study was to fabricate an antibacterial and degradable scaffold that may be used in the field of skin regeneration. To reach the degradation criterion for the biocompatible polyurethane (PUR), obtained by using amorphous α,ω-dihydroxy(ethylene-butylene adipate) macrodiol (PEBA), was used and processed with so-called “fast-degradable” polymer polylactide (PLA) (5 or 10 wt %). To meet the antibacterial requirement obtained, hybrid PUR-PLA scaffolds (HPPS) were modified with ciprofloxacin (Cipro) (2 or 5 wt %) and the fluoroquinolone antibiotic inhibiting growth of bacteria, such as Pseudomonas aeruginosa, Escherichia coli, and Staphylococcus aureus, which are the main causes of wound infections. Performed studies showed that Cipro-modified HPPS, obtained by using 5% of PLA, possess suitable mechanical characteristics, morphology, degradation rates, and demanded antimicrobial properties to be further developed as potential scaffolds for skin tissue engineering.

Cytowania

  • 5

    CrossRef

  • 5

    Web of Science

  • 5

    Scopus

Cytuj jako

Pełna treść

pobierz publikację
pobrano 15 razy
Wersja publikacji
Accepted albo Published Version
Licencja
Creative Commons: CC-BY otwiera się w nowej karcie

Słowa kluczowe

Informacje szczegółowe

Kategoria:
Publikacja w czasopiśmie
Typ:
artykuły w czasopismach
Opublikowano w:
Polymers nr 12, strony 1 - 18,
ISSN: 2073-4360
Język:
angielski
Rok wydania:
2020
Opis bibliograficzny:
Carayon I., Terebieniec A., Łapiński M., Filipowicz N., Kucińska-Lipka J.: Ciprofloxacin-modified degradable hybrid polyurethane-polylactide porous scaffolds developed for potential use as an antibacterial scaffold for regeneration of skin// Polymers -Vol. 12,iss. 1 (2020), s.1-18
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.3390/polym12010171
Bibliografia: test
  1. Esteban-vives, R.; Young, M.T.; Ziembicki, J.; Corcos, A.; Gerlach, C. Effects of wound dressings on cultured primary keratinocytes. Burns 2016, 42, 81-90. [CrossRef] [PubMed] otwiera się w nowej karcie
  2. Wohlsein, P.; Peters, M.; Schulze, C.; Baumga, W. Thermal Injuries in Veterinary Forensic Pathology. Vet. Pathol. 2016, 53, 1001-1017. [CrossRef] [PubMed] otwiera się w nowej karcie
  3. Kim, M.; Evans, D. Tissue engineering: The future of stem cells. Top. Tissue Eng. 2005, 2, 1-22.
  4. Brekke, J.H.; Toth, J.M. Principles of tissue engineering applied to programmable osteogenesis. J. Biomed. Mater. Res. 1998, 43, 380-398. [CrossRef] otwiera się w nowej karcie
  5. Gurtner, G.C.; Callaghan, M.J.; Longaker, M.T. Progress and potential for regenerative medicine. Annu. Rev. Med. 2007, 58, 299-312. [CrossRef] otwiera się w nowej karcie
  6. Gurtner, G.C.; Werner, S.; Barrandon, Y.; Longaker, M.T. Wound repair and regeneration. Nature 2008, 453, 314. [CrossRef] otwiera się w nowej karcie
  7. Feinberg, A.W. Engineered tissue grafts: Opportunities and challenges in regenerative medicine. Wiley Interdiscip. Rev. Syst. Biol. Med. 2012, 4, 207-220. [CrossRef] otwiera się w nowej karcie
  8. Kucinska-Lipka, J.; Gubanska, I.; Janik, H.; Pokrywczynska, M.; Drewa, T. L-ascorbic acid modified poly(ester urethane)s as a suitable candidates for soft tissue engineering applications. React. Funct. Polym. 2015, 97, 105-115. [CrossRef] otwiera się w nowej karcie
  9. Lipka, J.K.; Lewandowska, I.G.A. Antibacterial polyurethanes, modified with cinnamaldehyde, as potential materials for fabrication of wound dressings. In Polymer Bulletin; Springer: Berlin/Heidelberg, Germany, 2018.
  10. Kucińska-Lipka, J.; Gubanska, I.; Skwarska, A. Microporous polyurethane thin layer as a promising scaffold for tissue engineering. Polymers 2017, 9, 277. [CrossRef] [PubMed] otwiera się w nowej karcie
  11. Heureux, L.; Fricain, J.; Catros, S.; Le Nihouannen, D. Characterization of printed PLA scaffolds for bone tissue engineering. J. Biolmed. Mater. Res. 2018, 106, 887-894.
  12. Li, L.; Li, Q.; Yang, J.; Sun, L.; Guo, J.; Yao, Y.; Zhong, L.; Li, D. Enhancement in mechanical properties and cell activity of polyurethane scaffold derived from gastrodin. Mater. Lett. 2018, 228, 435-438. [CrossRef] otwiera się w nowej karcie
  13. Mi, H.; Jing, X.; Yu, E.; Wang, X.; Li, Q.; Turng, L. Manipulating the structure and mechanical properties of thermoplastic polyurethane/polycaprolactone hybrid small diameter vascular scaff olds fabricated via electrospinning using an assembled rotating collector. J. Mech. Behav. Biomed. Mater. 2018, 78, 433-441. [CrossRef] [PubMed] otwiera się w nowej karcie
  14. Barnes, C.P.; Sell, S.A.; Boland, E.D.; Simpson, D.G.; Bowlin, G.L. Nanofiber technology: Designing the next generation of tissue engineering scaffolds. Adv. Drug Deliv. Rev. 2007, 59, 1413-1433. [CrossRef] [PubMed] otwiera się w nowej karcie
  15. Gubanska, I.; Kucinska-Lipka, J.; Janik, H. The influence of amorphous macrodiol, diisocyanate type and L-ascorbic acid modifier on chemical structure, morphology and degradation behavior of polyurethanes for tissue scaffolds fabrication. In Polymer Degradation and Stability; otwiera się w nowej karcie
  16. Mikos, A.G.; Herring, S.W.; Ochareon, P.; Elisseeff, J.; Lu, H.H.; Kandel, R.; Schoen, F.J.; Toner, M.; Mooney, D.; Atala, A.; et al. Engineering complex tissues. Tissue Eng. 2006, 12, 3307-3339. [CrossRef] [PubMed] otwiera się w nowej karcie
  17. Palmiero, C.; Imparato, G.; Urciuolo, F.; Netti, P. Engineered dermal equivalent tissue in vitro by assembly of microtissue precursors. Acta Biomater. 2010, 6, 2548-2553. [CrossRef] otwiera się w nowej karcie
  18. Urciuolo, F.; Imparato, G.; Totaro, A. Building a tissue in vitro from the bottom up: Implications in regenerative medicine. Methodist Debakey Cardiovasc. J. 2013, 9, 213-217. [CrossRef] otwiera się w nowej karcie
  19. Fisher, M.B.; Mauck, R.L. Tissue Engineering and Regenerative Medicine: Recent Innovations and the Transition to Translation. Tissue Eng. Part B Rev. 2013, 19, 1-13. [CrossRef] otwiera się w nowej karcie
  20. Dong, Z.; Li, Y.; Zou, Q. Degradation and biocompatibility of porous nano-hydroxyapatite/polyurethane composite scaffold for bone tissue engineering. Appl. Surf. Sci. 2009, 255, 6087-6091. [CrossRef] otwiera się w nowej karcie
  21. Tatai, L.; Moore, T.G.; Adhikari, R. Thermoplastic biodegradable polyurethanes: The effect of chain extender structure on properties and in-vitro degradation. Biomaterials 2007, 28, 5407-5417. [CrossRef] otwiera się w nowej karcie
  22. Bose, S.; Roy, M.; Bandyopadhyay, A. Recent advances in bone tissue engineering scaffolds. Trends Biotechnol. 2012, 30, 546-554. [CrossRef] otwiera się w nowej karcie
  23. Liu, X.; Chen, W.; Gustafson, C.T.; Lee, A.; Ii, M.; Waletzki, B.E.; Yaszemski, M.J.; Lu, L. Tunable tissue sca ff olds fabricated by in situ crosslink in phase separation system. RSC Adv. R. Soc. Chem. 2015, 5, 100824-100833. [CrossRef] [PubMed] otwiera się w nowej karcie
  24. Middleton, J.C.; Tipton, A.J. Synthetic biodegradable polymers as orthopedic devices. Biomaterials 2000, 21, 2335-2346. [CrossRef] otwiera się w nowej karcie
  25. DW, H. scaffold-based bone engineering by using rapi prototyping technologies in virtual and rapid manufacturing. In Advanced Research in Virtual and Rapid Prototyping; Bartolo, J.B., Ed.; Taylor & Francis Group: Abingdon-on-Thames, UK, 2008; p. 65. otwiera się w nowej karcie
  26. Guelcher, S.A.; Srinivasan, A.; Dumas, J.E.; Didier, J.E.; McBride, S.; Hollinger, J.O. Synthesis, mechanical properties, biocompatibility, and biodegradation of polyurethane networks from lysine polyisocyanates. Biomaterials 2008, 29, 1762-1775. [CrossRef] [PubMed] otwiera się w nowej karcie
  27. Montini-Ballarin, F.; Caracciolo, P.C.; Rivero, G.; Abraham, G.A. In vitro degradation of electrospun poly(l-lactic acid)/segmented poly(ester urethane) blends. Polym. Degrad. Stab. 2016, 126, 159-169. [CrossRef] otwiera się w nowej karcie
  28. Ballarin, F.M.; Caracciolo, P.C.; Blotta, E.; Ballarin, V.L.; Abraham, G.A. Optimization of poly(L-lactic acid)/segmented polyurethane electrospinning process for the production of bilayered small-diameter nano fi brous tubular structures. Mater. Sci. Eng. C 2014, 42, 489-499. [CrossRef] otwiera się w nowej karcie
  29. Gudiño-rivera, J.; Medellín-rodríguez, F.J.; Ávila-orta, C.; Palestino-escobedo, A.G.; Sánchez-valdés, S. Structure/property relationships of poly(L-lactic acid)/mesoporous silica nanocomposites. J. Polym. 2013, 2013. [CrossRef] otwiera się w nowej karcie
  30. Ulery, B.D.; Nair, L.S.; Laurencin, C.T. Biomedical Applications of Biodegradable Polymers. J. Polym. Sci. Part. B Polym. Phys. 2011, 49, 832-864. [CrossRef] otwiera się w nowej karcie
  31. Lipsa, R.; Tudorachi, N.; Vasile, C. Poly(α-hydroxyacids ) in biomedical applications: Synthesis and properties of lactic acid polymers. e-Polymers 2010, 10. [CrossRef] otwiera się w nowej karcie
  32. Lasprilla, A.J.R.; Martinez, G.A.R.; Lunelli, B.H.; Jardini, A.L.; Maciel, R. Poly-lactic acid synthesis for application in biomedical devices-A review. Biotechnol. Adv. 2012, 30, 321-328. [CrossRef] otwiera się w nowej karcie
  33. Vats, A.; Tolley, Ã.N.S.; Polak, J.M.Ã.; Gough, J.E.Ã. Scaffolds and biomaterials for tissue engineering: A review of clinical applications. Clin. Otolaryngol. Allied Sci. 2003, 28, 165-172. [CrossRef] [PubMed] otwiera się w nowej karcie
  34. Elsawy, M.A.; Kim, K.; Park, J.; Deep, A. Hydrolytic degradation of polylactic acid(PLA) and its composites. Renew. Sustain. Energy Rev. 2017, 79, 1346-1352. [CrossRef] otwiera się w nowej karcie
  35. Adhikari, R.; Scientific, T.C. Biodegradable polyurethanes: Design, synthesis, properties and potential applications. In Biodegradable Polymers: Processing, Degradation and Applications; Nova Science Publishers: Hauppauge, NY, USA, 2011; pp. 431-470.
  36. Guelcher, S.A. Biodegradable polyurethanes: Synthesis and applications in regenerative medicine. Tissue Eng. Part. B Rev. 2008, 14, 11-19. [CrossRef] otwiera się w nowej karcie
  37. Mogensen, T.H. Pathogen recognition and inflammatory signaling in innate immune defenses. Clin. Microbiol. Rev. 2009, 22, 240-273. [CrossRef] [PubMed] otwiera się w nowej karcie
  38. Chen, L.; Deng, H.; Cui, H.; Fang, J.; Zuo, Z. Inflammatory responses and inflammation-associated diseases in organs. Oncotarget 2018, 9, 7204-7218. [CrossRef] [PubMed] otwiera się w nowej karcie
  39. Guo, S.; Dipietro, L.A. Factors affecting wound healing. J. Dent. Res. 2010, 89, 219-229. [CrossRef] otwiera się w nowej karcie
  40. Kwok, C.S.; Wan, C.; Hendricks, S.; Bryers, J.D.; Horbett, T.A.; Ratner, B.D. Design of infection-resistant antibiotic-releasing polymers: I. fabrication and formulation. J. Control. Release 1999, 62, 289-299. [CrossRef] otwiera się w nowej karcie
  41. Field, K.; Kerstein, M.D. Overview of wound healing in a moist environment. Am. J. Surg. 1994, 167, 2-6. [CrossRef] otwiera się w nowej karcie
  42. Anjum, S.; Arora, A.; Alam, M.S.; Gupta, B. Development of antimicrobial and scar preventive chitosan hydrogel wound dressings. Int. J. Pharm. 2016, 508, 92-101. [CrossRef] [PubMed] otwiera się w nowej karcie
  43. Vowden, K. Wound dressings: Principles and practice. In Surgery; Elsevier Ltd.: Amsterdam, The Netherlands, 2017; pp. 1-6. otwiera się w nowej karcie
  44. Koosehgol, S.; Ebrahimian-hosseinabadi, M.; Alizadeh, M.; Zamanian, A. Preparation and characterization of in situ chitosan/polyethylene glycol fumarate/thymol hydrogel as an effective wound dressing. Mater. Sci. Eng. C 2017, 79, 66-75. [CrossRef] [PubMed] otwiera się w nowej karcie
  45. Yari, A.; Yeganeh, H.; Bakhshi, H. Synthesis and evaluation of novel absorptive and antibacterial polyurethane membranes as wound dressing. J. Mater. Sci. Mater. Med. 2012, 23, 2187-2202. [CrossRef] [PubMed] otwiera się w nowej karcie
  46. Bergamo, R.; Buzatto, C.; Alberto, J.; Maria, Â. Electrospun multilayer chitosan scaffolds as potential wound dressings for skin lesions. Eur. Polym. J. 2017, 88, 161-170.
  47. Sikareepaisan, P.; Ruktanonchai, U.; Supaphol, P. Preparation and characterization of asiaticoside-loaded alginate films and their potential for use as effectual wound dressings. Carbohydr. Polym. 2011, 83, 1457-1469. [CrossRef] otwiera się w nowej karcie
  48. Unnithan, A.R.; Barakat, N.A.M.; Pichiah, P.B.T.; Gnanasekaran, G.; Nirmala, R.; Cha, Y.; Jung, C.H.; El-Newehy, M.; Kim, H.Y. Wound-dressing materials with antibacterial activity from electrospun polyurethane-dextran nanofiber mats containing ciprofloxacin HCl. Carbohydr. Polym. 2012, 90, 1786-1793. [CrossRef] [PubMed] otwiera się w nowej karcie
  49. Nagarwal, R.C.; Kant, S.; Singh, P.N.; Maiti, P.; Pandit, J.K. Polymeric nanoparticulate system: A potential approach for ocular drug delivery. J. Control. Release 2009, 136, 2-13. [CrossRef] [PubMed] otwiera się w nowej karcie
  50. Sinha, M.; Banik, R.M. Development of ciprofloxacin hydrochloride loaded poly(ethylene glycol)/chitosan scaffold as wound dressing. J. Porous Mater. 2013, 20, 799-807. [CrossRef] otwiera się w nowej karcie
  51. Bergman, B.; Bishop, M.C.; Bjerklund-johansen, T.E.; Botto, H.; Lobel, B.; Cruz, F.J.; Selvaggi, F.P. EAU guidelines for the management of urinary and male genital tract infectionstextsuperscript1. Eur. Urol. 2001, 40, 576-588.
  52. Zeiler, H.; Grohe, K.; Ag, B.; Ciprofloxacin, A.A. the in vitro and in vivo activity of ciprofloxacin. In Ciprofloxacin; Vieweg+Teubner Verlag: Wiesbaden, Germany, 1986; pp. 14-18. otwiera się w nowej karcie
  53. Dillen, K.; Vandervoort, J.; Van Den Mooter, G.; Verheyden, L.; Ludwig, A. Factorial design, physicochemical characterisation and activity of ciprofloxacin-PLGA nanoparticles. Int. J. Pharm. 2004, 275, 171-187. [CrossRef] otwiera się w nowej karcie
  54. Page, J.M.; Prieto, E.M.; Dumas, J.E.; Zienkiewicz, K.J.; Wenke, J.C.; Brown-Baer, P.; Guelcher, S.A. Biocompatibility and chemical reaction kinetics of injectable, settable polyurethane/allograft bone biocomposites. Acta Biomater. 2012, 8, 4405-4416. [CrossRef] otwiera się w nowej karcie
  55. Bessa, L.J.; Fazii, P.; Di Giulio, M.; Cellini, L. Bacterial isolates from infected wounds and their antibiotic susceptibility pattern: Some remarks about wound infection. Int. Wound J. 2015, 12, 47-52. [CrossRef] otwiera się w nowej karcie
  56. Boffito, M.; Sartori, S.; Ciardelli, G. Polymeric scaffolds for cardiac tissue engineering: Requirements and fabrication technologies. Polym. Int. 2014, 63, 2-11. [CrossRef] otwiera się w nowej karcie
  57. Janik, H.; Marzec, M. A review: Fabrication of porous polyurethane scaffolds. Mater. Sci. Eng. C 2015, 48, 586-591. [CrossRef] [PubMed] otwiera się w nowej karcie
  58. Silvestri, A.; Boffito, M.; Sartori, S.; Ciardelli, G. Biomimetic materials and scaffolds for myocardial tissue regeneration. Macromol. Biosci. 2013, 13, 984-1019. [CrossRef] otwiera się w nowej karcie
  59. Stachelek, S.J.; Alferiev, I.; Ueda, M.; Eckels, E.C.; Kevin, T.; Levy, R.J. Prevention of polyurethane oxidative degradation with phenolic-antioxidants covalently attached to the hard segments: Structure function. J. Biomed. Mater. Res. Part. A 2010, 94, 751-759. [CrossRef] [PubMed] otwiera się w nowej karcie
  60. Cetina-Diaz, S.M.; Chan-Chan, L.H.; Vargas-Coronado, R.F.; Cervantes-Uc, J.M.; Quintana-Owen, P.; Paakinaho, K.; Kellomaki, M.; Silvio, L.D.; Deb, S.; Cauich-Rodríguez, J.V. Physicochemical characterization of segmented polyurethanes prepared with glutamine or ascorbic acid as chain extenders and their hydroxyapatite composites. J. Mater. Chem. B 2014, 2, 1966-1976. [CrossRef] otwiera się w nowej karcie
  61. Tan, Z.; Tan, F.; Zhao, L.; Li, J. The Synthesis, Characterization and Application of Ciprofloxacin Complexes and Its Coordination with Copper, Manganese and Zirconium Ions. J. Cryst. Process Technol. 2012, 2, 55-63. [CrossRef] otwiera się w nowej karcie
  62. Yilgor, I.; Yilgor, E.; Guler, I.G.; Ward, T.C.; Wilkes, G.L. FTIR investigation of the influence of diisocyanate symmetry on the morphology development in model segmented polyurethanes. Polymer 2006, 47, 4105-4114. [CrossRef] otwiera się w nowej karcie
  63. Doolittle, J.; Su, H.-C.; Khatun, J.; Secrest, A.; Clark, M.; Ramkissoon, K.; Wolfgang, M.C.; Giddings, M.C. The development of ciprofloxacin resistance in pseudomonas aeruginosa involves multiple response stages and multiple proteins. Antimicrob. Agents Chemother. 2010, 54, 4626-4635.
  64. Kucinska-Lipka, J.; Gubanska, I.; Sienkiewicz, M. Thermal and mechanical properties of polyurethanes modified with L-ascorbic acid. J. Therm. Anal. Calorim. 2017, 127, 1631-1638. [CrossRef] otwiera się w nowej karcie
  65. Diridollou, S.; Patat, F.; Gens, F.; Vaillant, L.; Black, D.; Lagarde, J.M.; Gall, Y.; Berson, M. In vivo model of the mechanical properties of the human skin under suction. Skin Res. Technol. 2000, 6, 214-221. [CrossRef] otwiera się w nowej karcie
  66. Gallagher, A.J.; Ní Anniadh, A.; Bruyère, K.; Otténio, M.; Xie, H.; Gilchrist1, M.D. Dynamic tensile properties of human skin. In Proceedings of the 2012 IRCOBI Conference International Research Council on the Biomechanics of Injury, Dublin, Ireland, 12-14 Sepember 2012; pp. 494-502.
  67. Kucińska-Lipka, J.; Gubańska, I.; Janik, H. Gelatin-modified polyurethanes for soft tissue scaffold. Sci. World J. 2013, 2013. [CrossRef] otwiera się w nowej karcie
  68. © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). otwiera się w nowej karcie
Źródła finansowania:
  • This work was supported by the Gdansk University of Technology, Narutowicza St. 11/12, 80-233 Gdansk, Poland, Internal Funding No. 033206
Weryfikacja:
Politechnika Gdańska

wyświetlono 54 razy

Publikacje, które mogą cię zainteresować

Meta Tagi