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Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions

Abstrakt

In this paper, an investigation into detecting immunosuppressive medicine in aqueous solutions using a spectrometry-based technique is described. Using optical transmissive spectrometry, absorbance measurements in the spectra range from 250 nm to 1000 nm were carried out for different cyclosporine A (CsA) concentrations in aqueous solutions. The experiment was conducted for samples both with and without interferent substances—glucose and sodium chloride. Using a dedicated algorithm, the measured data was analyzed and a high correlation coefficient R2 = 0.8647 was achieved. The experiment showed that the described technique allowed for the detection of various CsA concentration levels in a selective, label-free and simple way. This method could be used in medicine, veterinary medicine and laboratory diagnostics.

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Informacje szczegółowe

Kategoria:
Publikacja w czasopiśmie
Typ:
artykuł w czasopiśmie wyróżnionym w JCR
Opublikowano w:
SENSORS nr 18, wydanie 7, strony 1 - 9,
ISSN: 1424-8220
Język:
angielski
Rok wydania:
2018
Opis bibliograficzny:
Marzejon M., Kosowska M., Majchrowicz D., Bułło-Piontecka B., Wąsowicz M., Jędrzejewska-Szczerska M.: Optical-Spectrometry-Based Method for Immunosuppressant Medicine Level Detection in Aqueous Solutions// SENSORS. -Vol. 18, iss. 7 (2018), s.1-9
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.3390/s18072001
Bibliografia: test
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Weryfikacja:
Politechnika Gdańska

wyświetlono 38 razy

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