Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation - Publikacja - MOST Wiedzy

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Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation

Abstrakt

In brain studies, the function of the cerebrospinal fluid (CSF) awakes growing interest, particularly related to studies of the glymphatic system in the brain, which is connected with the complex system of lymphatic vessels responsible for cleaning the tissues. The CSF is a clear, colourless liquid including water (H2O) approximately with a concentration of 99 %. In addition, it contains electrolytes, amino acids, glucose, and other small molecules found in plasma. The CSF acts as a cushion behind the skull, providing basic mechanical as well as immunological protection to the brain. Disturbances of the CSF circulation have been linked to several brain related medical disorders, such as dementia. Our goal is to develop an in vivo method for the non-invasive measurement of cerebral blood flow and CSF circulation by exploiting optical and capacitive sensing techniques simultaneously. We introduce a prototype of a wearable probe that is aimed to be used for long-term brain monitoring purposes, especially focusing on studies of the glymphatic system. In this method, changes in cerebral blood flow, particularly oxy- and deoxyhaemoglobin, are measured simultaneously and analysed with the response gathered by the capacitive sensor in order to distinct the dynamics of the CSF circulation behind the skull. Presented prototype probe is tested by measuring liquid flows inside phantoms mimicking the CSF circulation.

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Copyright (2017 SPIE)

Informacje szczegółowe

Kategoria:
Aktywność konferencyjna
Typ:
materiały konferencyjne indeksowane w Web of Science
Tytuł wydania:
Conference on Dynamics and Fluctuations in Biomedical Photonics XIV
Język:
angielski
Rok wydania:
2017
Opis bibliograficzny:
Myllylä T., Vihriälä E., Pedone M., Korhonen V., Surażyński Ł., Wróbel M., Zienkiewicz A., Hakala J., Sorvoja H., Lauri J., Fabritius T., Jędrzejewska-Szczerska M., Kiviniemi V., Meglinski I..: Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation, W: Conference on Dynamics and Fluctuations in Biomedical Photonics XIV, 2017, SPIE,.
DOI:
Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1117/12.2251977
Bibliografia: test
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Weryfikacja:
Politechnika Gdańska

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