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The comparison of antioxidant properties and nutrigenomic redox-related activities of vitamin C, C-vitamers, and other common ascorbic acid derivatives
Abstrakt
The term ‘vitamin C’ describes a group of compounds with antiscorbutic activity of L-ascorbic acid (AA). Despite AA’s omnipresence in plant-derived foods, its derivatives have also been successfully implemented in the food industry as antioxidants, including the D-isomers, which lack vitamin C activity. This study aimed to determine the relationship between redox-related activities for five derivatives of AA using electrochemical, chemical, and biological approaches. Here we report that AA, C-vitamers, and other commonly consumed AA derivatives differ in their redox-related activities. As long as the physiological range of concentrations was maintained, there was no simple relationship between their redox properties and biological activity. Clear distinctions in antioxidant activity were observed mostly at high concentrations, which were strongly correlated with electrochemical and kinetic parameters describing redox-related properties of the studied compounds. Despite obvious similarities in chemical structures and antioxidant activity, we showed that C-vitamers may exhibit different nutrigenomic effects. Together, our findings provide a deeper insight into so far underinvestigated area combining chemical properties with biological activities of commonly applied AA derivatives.
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Web of Science
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6
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Autorzy (10)
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Monika Kuczyńska dr mgr inż.
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Muhammad Asaduzzamana
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Informacje szczegółowe
- Kategoria:
- Publikacja w czasopiśmie
- Typ:
- artykuły w czasopismach
- Opublikowano w:
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FREE RADICAL BIOLOGY AND MEDICINE
nr 209,
strony 239 - 251,
ISSN: 0891-5849 - Język:
- angielski
- Rok wydania:
- 2023
- Opis bibliograficzny:
- Jakubek P., Suliborska K., Kuczyńska M., Asaduzzamana M., Parchem K., Koss-Mikołajczyk I., Kusznierewicz B., Chrzanowski W., Namieśnik J., Bartoszek-Pączkowska A.: The comparison of antioxidant properties and nutrigenomic redox-related activities of vitamin C, C-vitamers, and other common ascorbic acid derivatives// FREE RADICAL BIOLOGY AND MEDICINE -,iss. 209 (2023), s.239-251
- DOI:
- Cyfrowy identyfikator dokumentu elektronicznego (otwiera się w nowej karcie) 10.1016/j.freeradbiomed.2023.10.400
- Źródła finansowania:
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- Publikacja bezkosztowa
- Weryfikacja:
- Politechnika Gdańska
wyświetlono 50 razy
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