The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Alexandra Rafeletou; Jenni Viivi Linnea Niemi; Francisco Alejandro Lagunas-Rangel; Wen Liu; Błażej Kudłak; Helgi B. Schiöth

doi:10.1016/j.scitotenv.2024.170999

The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures

Abstrakt

Substances that can absorb sunlight and harmful UV radiation such as organic UV filters are widely used in cosmetics and other personal care products. Since humans use a wide variety of chemicals for multiple purposes it is common for UV filters to co-occur with other substances either in human originating specimens or in the environment. There is increasing interest in understanding such co-occurrence in form of potential synergy, antagonist, or additive effects of biological systems. This review focuses on the collection of data about the simultaneous occurrence of UV filters oxybenzone (OXYB), ethylexyl-methoxycinnamate (EMC) and 4-methylbenzylidene camphor (4-MBC) as well as other classes of chemicals (such as pesticides, bisphenols, and parabens) to understand better any such interactions considering synergy, additive effect and antagonism. Our analysis identified >20 different confirmed synergies in 11 papers involving 16 compounds.

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Autorzy (6)

Alexandra Rafeletou
- Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden
Jenni Viivi Linnea Niemi
- Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden
Francisco Alejandro Lagunas-Rangel
- Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden
Wen Liu
- Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden
Błażej Kudłak dr hab. inż.
Helgi B. Schiöth
- Department of Surgical Sciences, Functional Pharmacology and Neuroscience, Uppsala University, Uppsala, Sweden

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Kategoria:

Publikacja w czasopiśmie

Typ:

artykuły w czasopismach

Opublikowano w:

SCIENCE OF THE TOTAL ENVIRONMENT nr 928,
ISSN: 0048-9697

Język:

angielski

Rok wydania:

2024

Opis bibliograficzny:

Rafeletou A., Niemi J. V. L., Lagunas-Rangel F. A., Liu W., Kudłak B., Schiöth H. B.: The exposure to UV filters: Prevalence, effects, possible molecular mechanisms of action and interactions within mixtures// SCIENCE OF THE TOTAL ENVIRONMENT -Vol. 928, (2024), s.170999-

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