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Wyniki wyszukiwania dla: PANEL DATA
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From tryptophan to novel mitochondria-disruptive agent, synthesis and biological evaluation of 1,2,3,6-tetrasubstituted carbazoles
PublikacjaMitochondrial targeting plays an important role in anticancer therapy. The Mn(III)-promoted cyclization of 5- (1H-indol-3-yl)-3-oxopentanoic acid allow to obtain novel substituted carbazole derivatives that can act as mitochondria-disruptive agents. The starting materials used for the synthesis of these new aminocarbazoles are oxopentanoate derivatives of tryptophan. The scope and limitation of this method of synthesis are determined...
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Does pandemic denial help or harm? Belief in COVID-19 and experience of it affect psychological consequences of using neurotic defence mechanisms
PublikacjaObjective: The COVID-19 pandemic may activate thoughts of death, leading to aversive psychological states. In such situations, defence mechanisms emerge; however, their adaptability depends on many factors. The aim of the study was to investigate the relationship between neurotic defence style and depressive symptoms. We assumed that the sense of coherence underlies this correlation and investigated how both believing (or not)...
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Enhancement of lift and drag performances of a NACA0012 airfoil by multi-DBD plasma actuator with additional floating interelectrodes
PublikacjaIt is clear that the improvement of aircraft aerodynamic performances is currently and will continue to be a significant area of research for the aeronautical industry. The current study is focused on theenhancement of aerodynamic airfoil performances by using a multi-DBD plasma actuator mounted around the model leading-edge. Experiments have been conducted at the University of Orleans, in the 2 m x 2 m test section of a large...
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Financial Markets and Bankruptcy Systems: Is there a Relationship?
PublikacjaPurpose: Filling the cognitive gap in the theory of ex-post transaction costs, i.e., at the stage of enforcing market transactions by examining the relationship between friendliness/severity of the bankruptcy and restructuring law towards debtors, the level of development of financial markets, the effectiveness of the judicial system and the rate of debt recovery. Design/Methodology/Approach: In the research, the following methods...
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Reshaping financial systems: The role of ICT in the diffusion of financial innovations – Recent evidence from European countries
PublikacjaExchange-traded funds (ETFs) are among the fastest-growing types of innovative financial products. The emergence and spread of these instruments have been facilitated by the digital revolution. Information and communication technology (ICT) is profoundly reshaping the global economic landscape, laying solid foundations for unrestricted and unbounded flows of information and knowledge, eliminating information asymmetries, and furthering...
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Uncovering the invisible barriers to women’s success
PublikacjaIn the area of science and higher education, as in business and politics, the job situation of women is improving, and the percentage of women on executive positions is increasing. However, there is still a serious underrepresentation of women in the highest decision-making bodies. Ladies also take part in the strategic institutional events less frequently. There are still serious disproportions in academic and management positions,...
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The impact of equity pledge on inefficient investment: a perspective from family entrepreneurship
PublikacjaAs an efficient and convenient financing method, equity pledges may have a heterogeneous impact on the inefficient investment of family firms. In order to verify this point, this paper takes A-share listed family enterprises from 2010 to 2021 as a research sample. It conducts an empirical test on the impact of equity pledges on inefficient investment in family firms by constructing a panel regression model. The results show...
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System sterowania indukcyjnym silnikiem liniowym na bieżni liniowej - analiza problemów działania wykorzystanych protokołów komunikacyjnych
PublikacjaW artykule opisano stanowisko laboratoryjne z silnikiem liniowym na bieżni liniowej znajdujące się w Katedrze Energoelektroniki i Maszyn Elektrycznych na Wydziale Elektrotechniki i Automatyki Politechniki Gdańskiej oraz omówiono, w jaki sposób rozwiązano problemy związane z działaniem wykorzystanych w systemie sterowania protokołów komunikacyjnych. Stanowisko ma charakter dydaktyczny. W skład stanowiska wchodzi indukcyjny silnik...
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The effect of numerical 2D and 3D FEM element modelling on strain and stress distributions at laser weld notches in steel sandwich type panels
PublikacjaLike other means of transport, merchant ships face the problem of increasing requirements concerning the environment protection, which, among other issues, implies the reduction of fuel consumption by the ship. Here, the conventional approach which consists in making use of higher strength steels to decrease the mass of the ship hull can be complemented by the use of new steel structures of sandwich panel type. However, the lack...
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IP & Innovation Day: od nauki do biznesu
WydarzeniaCentrum Transferu Technologii PG zaprasza do udziału w bezpłatnym wydarzeniu poświęconym innowacyjności, ochronie własności intelektualnej i komercjalizacji wyników badań naukowych. Obowiązuje rejestracja.
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What drives sustainable investing? Adoption determinants of sustainable investing exchange-traded funds in Europe
PublikacjaDespite the growing interest in various topics related to sustainable (ESG) investing, some issues remain understudied, such as the determinants of their utilization at the macro level. This paper contributes to the state of knowledge two-directionally. First, it shows the development of sustainable investing exchange-traded funds (ETFs) in European countries. Second, it traces the significant determinants of adopting sustainable...
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Is mesh fixation necessary in laparoendoscopic techniques for M3 inguinal defects? An experimental study.
Publikacjarepairs, in case of large direct hernias (M3) mesh fixation is recommended to reduce recurrence risk. Despite lack of highquality evidence, the recommendation was upgraded to strong by expert panel. The authors conducted a research experiment to verify the hypothesis that it is possible to preserve the mesh in the operating field in large direct hernias (M3) without the need to use fixing materials. Method The authors conducted...
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Optimization of the distance between the vertical plates in the convective air heat exchanger
PublikacjaThis paper examines the influence of the distance between vertical plates on the intensity of free convective heat transfer along with the optimization of this distance. Experimental tests were carried out for one model channel of such an heat exchanger with widths , 0.085 and 0.18 m. This channel, open at the top and sides, was formed by two isothermal symmetrically heated parallel vertical plates of dimensions m and m. The influence...
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MRI assessment of ectopic fat accumulation in pancreas, liver and skeletal muscle in patients with obesity, overweight and normal BMI in correlation with the presence of central obesity and metabolic syndrome
PublikacjaPurpose: Obesity, defined as a body mass index (BMI) exceeding 30 kg/m2, is a serious health problem, which can be called an epidemic on a global scale and is one of the most important causes of preventable death. The aim of this study was to assess ectopic fat accumulation in pancreas, liver and skeletal muscle in patients with obesity, overweight and normal BMI in correlation with metabolic syndrome (MetS). Patients and methods:...
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YES! Gdańsk 2018 – konferencja Studenckiego Koła SEP
WydarzeniaStudenckie Koło Stowarzyszenia Elektryków Polskich działające na Wydziale Elektrotechniki i Automatyki PG zaprasza na organizowane przez studentów wydarzenie YES! Gdańsk 2018.
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Termin zgłaszania wystapień do eTEE 2022
Wydarzenia8. ogólnopolska konferencja "e-Technologie w Kształceniu Inżynierów". Zgłaszanie propozycji wystapień w zakładce "Zgłaszanie abstraktów" na stronie konferencji eTEE: www.pg.edu.pl/etee.
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Post-Effort Changes in Autophagy- and Inflammation-Related Gene Expression in White Blood Cells of Healthy Young Men
PublikacjaAcute, strenuous physical exertion requiring high levels of energy production induces the production of reactive oxygen species and metabolic disturbances that can damage the mitochondria. Thus, selective autophagic elimination of defective mitochondria may improve resistance to oxidative stress and potentially to inflammation. The main goal of this study was to evaluate the impacts of intense effort on changes in the expression...
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Fast Low-fidelity Wing Aerodynamics Model for Surrogate-Based Shape Optimization
PublikacjaVariable-fidelity optimization (VFO) can be efficient in terms of the computational cost when compared with traditional approaches, such as gradient-based methods with adjoint sensitivity information. In variable-fidelity methods, the directoptimization of the expensive high-fidelity model is replaced by iterative re-optimization of a physics-based surrogate model, which is constructed from a corrected low-fidelity model. The success...
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Determinants of the incidence of non-academic staff in European and US HEIs
PublikacjaIn this article, we contribute to the scant literature covering quantitative studies on the determinants of the non-academic staff incidence in higher education institutions by analysing how the proportion of non-academic staff is related to key features such as size, prestige, year of foundation and financial structure of universities. We apply nonlinear regression analysis to compare HEIs across Europe and the USA, taking into...
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Application of gas chromatography,mass spectrometry and olfactometry for quality assessment of selected food products = Zastosowanie chromatografii gazowej, spektrometrii mas i olfaktometrii w ocenie jakości wybranych produktów spożywczych
PublikacjaStosując mikroekstrakcję do fazy stacjonarnej z fazy nadpowierzchniowej jako metodę przygotowania próbek i chromatografię gazową (GC) ze spektrometrią mas (MS) i olfaktometrią (O) jako metodę oznaczeń końcowych oznaczono lotne związki w spirytusach i miodach. Identyfikację przeprowadzono przez porównanie widm masowych z widmami z biblioteki NIST. Dodatkowo, wykrywane przez panel oceniający związki zapachowe rejestrowano w formie...
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Stalowe panele sandwicz w konstrukcjach okrętowych
PublikacjaDążenie do tego, aby nowe konstrukcje pojazdów takich jak statki czy pociągi były coraz szybsze, lżejsze i większe wywołuje konieczność poszukiwania innowacyjnych rozwiązań strukturalnych. Ujmując rzecz ogólnie, w celu realizacji tego postulatu, można iść w jednym z dwóch kierunków: poszukiwać nowych rozwiązań konstrukcyjnych czy też technologicznych, albo stosować nowe materiały. Oba podejścia są zazwyczaj wzajemnie ze sobą powiązane:...
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Net-zero policy and forward default risk in the energy sector:Evidence of corporate environmentalism using (a)symmetricmodels
PublikacjaThis study aims to examine the impact of the net-zero policy on forward default risk atthe firm level within the energy sector of the US, spanning over the period 2007–2021.The research employs Panel Vector Autoregression (PVAR) modeling, as well as linearand non-linear Autoregressive Distributed Lag (ARDL) models to investigate this rela-tionship. The findings suggest that the implementation of net-zero policy measures canhave...
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Burnout as a State: Random-Intercept Cross-Lagged Relationship Between Exhaustion and Disengagement in a 10-Day Study
PublikacjaBackground: Burnout has been traditionally seen as a chronic and stable state in response to prolonged stress. However, measures of momentary burnout are not well established, even though the within-person approach suggests that the symptoms of burnout may vary from day to day for the same employee. The aim of this study is to examine the daily inter- and intra-personal variability of the symptoms of burnout and the cross-lagged relationship...
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DEMO DAY programu Startup School One
WydarzeniaGdańsk Tech Startup School zaprasza na DEMO DAY, czyli prezentację zespołów, które ukończyły 6. edycję programu Startup School One. Uczestników wydarzenia obowiązuje rejestracja.
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Konferencja „Biznes i uczelnia w dążeniu do jakości"
WydarzeniaZapraszamy na konferencję „Biznes i uczelnia w dążeniu do jakości”, której częścią będzie panel dyskusyjny pt. „Kierunki współpracy biznesu i uczelni w zakresie doskonalenia jakości”.
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Carbonic anhydrase inhibitors. Synthesis, and molecular structure of novel series N-substituted N'-(2-arylmethylthio-4-chloro-5- methylbenzenesulfonyl)guanidines and their inhibition of human cytosolic isozymes I and II and the transmembrane tumor-associated isozymes IX and XII
PublikacjaA series of novel N-substituted N'-(2-arylmethylthio-4-chloro-5-methylbenzenesulfonyl)guanidines 9 e41 have been synthesized and investigated as inhibitors of four isoforms of zinc enzyme carbonic anhydrase (CA.EC 4.2.1.1), that is the cytosolic CA I and II, and cancer-associated isozymes CA IX and XII. Against the human CA I investigated compounds showed KI in the range of 87e6506 nM, toward hCA II ranging from 7.8 to 4500 nM,...
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Deep eutectic solvent enhances antibacterial activity of a modular lytic enzyme against Acinetobacter baumannii
PublikacjaIn this study, we evaluated the combined effect between MLE-15, a modular lytic enzyme composed of four building blocks, and reline, a natural deep eutectic solvent. The bioinformatic analysis allowed us to determine the spatial architecture of MLE-15, whose components were bactericidal peptide cecropin A connected via a flexible linker to the cell wall binding domain (CBD) of mesophilic 201ϕ2 − 1 endolysin and catalytic domain...
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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
PublikacjaA series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, 1H- and 13NMR, as well as MS spectra. X-ray crystal analysis of the representative 2-(1H-indol-2-yl)-3-acrylonitrile 2l showed that the acrylonitrile double bond was Z-configured. All...
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The antitumor compound triazoloacridinone C-1305 inhibits FLT3 kinase activity and potentiates apoptosis in mutant FLT3-ITD leukemia cells.
PublikacjaAim: FMS-like receptor tyrosine kinase (FLT3) is expressed in some normal hematopoietic cell types and plays an important role in the pathogenesis of acute myeloid leukemia (AML). In this study, we examined the effects of triazoloacridinone C-1305, an antitumor compound, on AML cells with different FLT3 status in vitro. Methods: A panel of human leukemic cell lines with different FLT3 status was used, including FLT3 internal tandem...
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Novel Resveratrol-Based Substrates for Human Hepatic, Renal, and Intestinal UDP-Glucuronosyltransferases
PublikacjaTrans-Resveratrol (tRes) has been shown to have powerful antioxidant, anti-inflammatory, anti-carcinogenic, and anti-aging properties; however, its use as a therapeutic agent is limited by its rapid metabolism into its conjugated forms by UDP-Glucuronosyltransferases (UGTs). The aim of the current study was to test the hypothesis that the limited bioavailability of tRes can be improved by modifying its structure to create analogs...
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"Biznes i uczelnia w dążeniu do jakości" - Edukacja dla doskonalenia jakości Edu4QI
WydarzeniaWydział Zarządzania i Ekonomii Politechniki Gdańskiej, firma Flex oraz Fundacja Edukacyjne Centrum Doskonalenia zapraszają na konferencję „Biznes i uczelnia w dążeniu do jakości – Edukacja dla doskonalenia jakości Edu4QI”, której częścią będzie panel dyskusyjny pt. „Kierunki współpracy biznesu i uczelni w zakresie doskonalenia jakości”. Celem...