Wyniki wyszukiwania dla: DYE AGREGGATION

• Problem of aggregation in dye-DNA interaction, calorimetry studies

  Publikacja

  • A. Dopierała
  • P. Wrosz
  • J. Mazerski

  - Acta Biochimica Polonica - Rok 2010

  Nucleic acids are the biological target for many antimicrobial, antitumor and antiviral drugs. Ligand-DNA interactions can be classified into two major categories: 1. covalent binding, which can provide to intermolecular adducts, 2. physico-chemical interactions, which can be divided into intercalation (e.g. adriamycin) or groove binding (e.g. dystamycin). There are several methods to investigate interactions between drug and DNA....