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A novel method of Mycobacterium tuberculosis complex strain differentiation using polymorphic GC-rich gene sequences.
PublikacjaTuberculosis is one of the leading infectious diseases. In this work, a new genotyping method of Mycobacterium tuberculosis (Mtb) complex strain is presented. 27 Mtb genomes were analyzed for the presence of length polymorphism within polymorphic GC-rich gene sequences. Four genes, Rv3345c, Rv3507, Rv0747 and Rv3511, showing variation in length depending on the Mtb strain were selected for designing primer sequences flanking variable...
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Mycobacterium tuberculosis Complex and Mycobacterial Heat Shock Proteins in Lymph Node Tissue from Patients with Pulmonary Sarcoidosis
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Evaluation of multiple genetic markers for typing drug-resistant Mycobacterium tuberculosis strains from Poland
PublikacjaW publikacji przedstawiono wyniki genotypowania wielolekoopornych szczepów Mycobacterium tuberculosis izolowanych od pacjentów z Polski.
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Molecular characterization of drug-resistant Mycobacterium tuberculosis strains from Poland by use of multiple genetic markers
PublikacjaW pracy przedstawiono wyniki genotypowania wielolekoopornych szczepów Mycobacterium tuberculosis, izolowanych od pacjentów z Polski.
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PCR-Based Genotyping of Mycobacterium tuberculosis with New GC-Rich Repeated Sequences and IS6110 Inverted Repeats Used as Primers.
PublikacjaW pracy przedstawiono nową metodę genotypowania Mycobacterium tuberculosis. Zastosowanie oligonukleotydu Mtb1 5'-CCG-GCG-GGG-CCG-GCG-G lub Mtb2 5'-CGG-CGG-CAA-CGG-CGG-C wraz z oligonukleotydami specyficznymi do terminalnych sekwencji elementu insercyjnego IS6110 pozwala na różnicowanie szczepów Mycobacterium tuberculosis w metodzie PCR. Opracowana metoda może być wykorzystana w badaniach epidemiologicznych gruźlicy.
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Antimicrobial Activity of Honey
PublikacjaHoney has had a valued place in traditional medicine for centuries. It was used to overcome liver, cardiovascular and gastrointestinal problems and for treatment of some types of infectious disease. Particularly, good results were achieved in the case of application of this product for therapy of infected, difficult to heal wounds. The high health-promoting properties of honey have been recently confirmed in many research investigations....
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Acid-catalysed synthesis of oxathiolone fused chalkones. Comparison of their activity toward various microrganisms and human cancer lines
PublikacjaOtrzymano podstawione pochodne oksationolowych sprzężonych chalkonów w wyniku kondensacji 4-acetylo-5-metoksy-2-0ksobenz[1,3]oksatiolu z aldehydem benzoesowym w środowisku kwaśnym. Badano właściwości biologiczne otrzymanych związków. Trzy z otrzymanych pochodnych wykazały umiarkowaną aktywność wobec komórek HeLa, dwa były aktywne wobec Micrococcus luteus i Staphylococcus aureus, a jeden wobec Mycobacterium tuberculosis.
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Antimicrobial molecular nanocarrier–drug conjugates
PublikacjaMany antimicrobial drugs are poorly active against pathogenic microbes causing intracellular infections, such as Mycobacterium tuberculosis or Plasmodium falciparum. On the other hand, several known antimicrobial agents are not effective enough because of their limited cellular penetration. A common feature of both challenges is the inability of an active agent to cross the biological membrane(s). One of the possible approaches...
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Józef Kur prof. dr hab.
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Isolation and identification of Mycobacterium avium subspecies silvaticum from a horse
PublikacjaPo raz pierwszy opracowano metodę identyfikacji Mycobacterium avium subsp. silvaticum na podstawie analizy sekwencji DNA alfa antygenu. Zastosowanie enzymu HhaI do trawienia produktu PCR z uzyskanego z udziałem starterów specyficznych wobec genu kodującego alfa antygen pozwoliło na identyfikację Mycobacterium avium subsp. silvaticum. Opracowana nowa metoda pozwala na prowadzenie badań epidemiologicznych bezpośrednio z próbek pochodzących...
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PCR amplification with primers based on IS2404 and GC-rich repeated sequence reveals polymorphism in Mycobacterium ulcerans
PublikacjaOpracowano prostą w wykonaniu metodę genotypowania szczepów bakterii z gatunku Mycobacterium ulcerans. Polimorfizm genetyczny 32 badanych izolatów Mycobacterium ulcerans odzwierciedla ich geograficzne pochodzenie z rejonów Afryki Centralnej, Ameryki Południowej i Łacińskiej, Azji Południowo-Wschodniej, Malezji oraz Australii.
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One-tube cell lysis and DNA extraction procedure for PCR based detection of Mycobacterium ulcerans in aquatic insects, molluscs and fish.
PublikacjaMycobacterium ulcerans jest bakterią wywołującą choroby skóry u ludzi i zwierząt. W trakcie prowadzonych badań opracowano prostą w wykonaniu metodę ekstrakcji DNA Mycobacterium ulcerans z próbek środowiskowych oraz klinicznych. Opracowana metoda izolacji DNA może być przydatna w badaniu źródeł infekcji oraz dróg szerzenia się Mycobacterium ulcerans.
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TUBERCULOSIS
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Tomasz Zubowicz dr inż.
OsobyTomasz Zubowicz has received his M.Sc. Eng. degree in Control Engineering from the Faculty of Electrical and Control Engineering at the Gda{\'n}sk University of Technology (GUT) in $2008$. He received his Ph.D. Eng. (Hons.) in the field of Control Engineering from the same faculty in $2019$. In $2012$ he became a permanent staff member at the Department of Intelligent Control and Decision Support Systems at GUT and a member of...
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Decreasing Vaccination Coverage Against Hepatitis B and Tuberculosis in Newborns
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Complex Steel Structures 2022
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Complex Manifolds
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Complex Systems
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Tuberculosis and Respiratory Diseases
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Indian Journal of Tuberculosis
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Multipath Complex Root Tracing
PublikacjaThe problem of multipath root tracing is being addressed in this communication. The self-adaptive complex root tracing algorithm, which was previously utilized for the investigation of various propagation and radiation problems, is analyzed here for the cases when the traced characteristic bifurcates. A procedure of multiroute detection is proposed and demonstrated on the coaxially loaded cylindrical waveguide example.
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Complex Steel Structures (2022/23)
Kursy Online -
Complex Steel Structures (2023/24)
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Properties and interpretation of Instantaneous Complex Frequency
PublikacjaThe concept of Instantaneous Complex Frequency (ICF) was first defined by Lindon and developed mainly in works of two authors S. Hahn and M. Rojewski. Although it is not widely used in signal analysis, ICF was already used as a complex signal representation in the verification of handwritten signatures, pitch estimation, symbol timing recovery in PSK receiver and in detection of anomalies in data transmission. It should be noted,...
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Instantaneous complex frequency for pipeline pitch estimation
PublikacjaIn the paper a pipeline algorithm for estimating the pitch of speech signal is proposed. The algorithm uses instantaneous complex frequencies estimated for four waveforms obtained by filtering the original speech signal through four bandpass complex Hilbert filters. The imaginary parts of ICFs from each channel give four candidates for pitch estimates. The decision regarding the final estimate is made based on the real parts of...
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Complex Concrete Structures (CE) - 2021/2022
Kursy OnlineThe following issues in the field of concrete structures will be discussed in the lecture part: Mechanical properties of concrete and reinforcing steel; Calculation of reinforced concrete cross-sections bending; Calculation of reinforced concrete cross-sections shear; Serviceability limit state in reinforced concrete structures; Reinforced concrete slabs, one-way and cross-reinforced; Reinforced concrete stairs; Reinforced...
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Complex Concrete Structures (CE) - 2023/2024
Kursy OnlineThe following issues in the field of concrete structures will be discussed in the lecture part: Mechanical properties of concrete and reinforcing steel; Calculation of reinforced concrete cross-sections bending; Calculation of reinforced concrete cross-sections shear; Serviceability limit state in reinforced concrete structures; Reinforced concrete slabs, one-way and cross-reinforced; Reinforced concrete stairs; Reinforced...
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ADVANCES IN COMPLEX SYSTEMS
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Complex & Intelligent Systems
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Journal of Complex Networks
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Journal of Complex Analysis
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Role of public space in designing complex urban structures
PublikacjaThe aim of this article is to present the main assumptions about design studios as held in the Faculty of Architecture at Gdańsk University of Technology (FA-GUT), Gdańsk, Poland, adapted to the development of key competencies in the urban planning of complex urban structures. One of these competencies is the design of public spaces. The main goal of the studios was to deliver knowledge of the role of public spaces in the design...
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Magdalena Apollo dr inż.
Osoby2017 - PhD in Civil Engineering, thesis: Risk management in construction investments related to urban regeneration projects, Gdansk University of Technology IX 2012–VI 2013 - Postgraduate Studies at Gdynia Maritime University: Research Project Management (IPMA D Certificate) 2010 – MSc in Management and Marketing, Gdansk University of Technology 2007 – MSc in Civil Engineering, Gdansk University of Technology 2007-2010 - structural...
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On root finding algorithms for complex functions with branch cuts
PublikacjaA simple and versatile method is presented, which enhances the complex root finding process by eliminating branch cuts and branch points in the analyzed domain. For any complex function defined by a finite number of Riemann sheets, a pointwise product of all the surfaces can be obtained. Such single-valued function is free of discontinuity caused by branch cuts and branch points. The roots of the new function are the same as the...
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Scanning the special section on technologies of large scale and complex systems
PublikacjaArtykuł wprowadza do Specjalnej Sekcji pt. Technologies for large scale and complex systems, zamieszczonej w czasopiśmie Annual Reviews in Control, Vol. 32, Issue 1 wydanego w kwietniu 2008. Specjalna sekcja zawiera artykuły będące rozszerzeniem referatów plenarnych wygłoszonych podczas 11th IFAC Symposium on Large Scale Complex Systems, które odbyło się w Gdańsku, Lipiec 2007r.
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N-point estimators of the Instantaneous Complex Frequency
PublikacjaIn this paper estimators of the instantaneous complex frequency (ICF) are presented and discussed. The differential approach for the estimation of the ICF is used, therefore the estimators are based on maximally flat N-point FIR filters: differential and delay. The investigation of the filter performance includes static characteristics of ICF estimation and the error of the ICF estimation in the discrete frequency domain.W pracy...
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Efficient Complex Root Finding Algorithm for Microwave and Optical Propagation Problems
PublikacjaArticle relates to the use of innovative root finding algorithm (on a complex plane) to study propagation properties of microwave and optical waveguides. Problems of this type occur not only in the analysis of lossy structures, but also in the study of complex and leaky modes (radiation phenomena). The proposed algorithm is simple to implement and can be applied for functions with singularities and branch cuts in the complex plane...
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Identity verification using complex representations of handwritten signature
PublikacjaThis paper is devoted to handwritten signature verification using the cross-correlation approach (adopted by the authors from telecommunications) and dynamic time warping. The following invariants of the handwritten signature: the net signature, the instantaneous complex frequency and the complex cepstrum are analyzed. The problem of setting the threshold for deciding whether the current signature is authentic or forged is discussed....
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Measurement of complex refractive index of human blood by low-coherence interferometry
PublikacjaIn this article, the usefulness of the optical technique for measurements of blood complex refractive index has been examined. Measurement of optical properties of human blood is difficult to perform because of its nonuniform nature. However, results of my investigation have shown the usefulness of low-coherencei nterferometry for measurement complex refractive index of human blood. Furthermore, mathematical analysis of spectrum...
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Numerical analysis of the ostiomeatal complex aeration using the CFD method
PublikacjaWe aimed to analyse ostiomeatal complex (OMC) aeration using the computational fluid dynamics (CFD) method of simulation based on human craniofacial computed tomography (CT) scans. The analysis was based on CT images of 2 patients: one with normal nose anatomy and one with nasal septal deviation (NSD). The Reynolds-Average Simulation approach and turbulence model based on linear eddy viscosity supplemented with the two-equation...
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Human voice modification using instantaneous complex frequency
PublikacjaThe paper presents the possibilities of changing human voice by modifying instantaneous complex frequency (ICF) of the speech signal. The proposed method provides a flexible way of altering voice without the necessity of finding fundamental frequency and formants' positions or detecting voiced and unvoiced fragments of speech. The algorithm is simple and fast. Apart from ICF it uses signal factorization into two factors: one fully...
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Novel Nonlinear High Order Technologies for Damage Diagnosis of Complex Assets
PublikacjaFor the first time worldwide, innovative techniques, generic non-linear higher-order unnormalized cross-correlations of spectral moduli, for the diagnosis of complex assets, are proposed. The normalization of the proposed techniques is based on the absolute central moments, that have been proposed and widely investigated in mathematical works. The existing higher-order, crosscovariances of complex spectral components are not sufficiently...
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Complex Root Finding Algorithm Based on Delaunay Triangulation
PublikacjaA simple and flexible algorithm for finding zeros of a complex function is presented. An arbitrary-shaped search region can be considered and a very wide class of functions can be analyzed, including those containing singular points or even branch cuts. The proposed technique is based on sampling the function at nodes of a regular or a self-adaptive mesh and on the analysis of the function sign changes. As a result, a set of candidate points...
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A modelling approach to the transport support for the harvesting and transportation complex under uncertain conditions
PublikacjaThe article proposes a modelling approach based on structural and parametric identification of the transport support of the harvesting and transportation complex. The efficiency and effectiveness of the proposed methods of structural and parametric identification for the development of a system for harvesting and transportation complex operation has been proved. A mathematical model based on fuzzy logic has been developed. It reflects...
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Global Complex Roots and Poles Finding Algorithm in C × R Domain
PublikacjaAn algorithm to find the roots and poles of a complex function depending on two arguments (one complex and one real) is proposed. Such problems are common in many fields of science for instance in electromagnetism, acoustics, stability analyses, spectroscopy, optics, and elementary particle physics. The proposed technique belongs to the class of global algorithms, gives a full picture of solutions in a fixed region ⊂ C × R and...
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Efficient Complex Root Tracing Algorithm for Propagation and Radiation Problems
PublikacjaAn efficient complex root tracing algorithm for propagation and radiation problems is presented. The proposed approach is based on a discretization of Cauchy’s Argument Principle and its generalization to the C × R space. Moreover, an engagement of the tracing process with a global root finding algorithm recently presented in the literature is performed. In order to confirm a validity and efficiency of the proposed technique, a...
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Multi-criterion, evolutionary and quantum decision making in complex systems
PublikacjaMulti-criterion, evolutionary and quantum decision making supported by the Adaptive Quantum-based Multi-criterion Evolutionary Algorithm (AQMEA) has been considered for distributed complex systems. AQMEA had been developed to the task assignment problem, and then it has been applied to underwater vehicle planning as another benchmark three-criterion optimization problem. For evaluation of a vehicle trajectory three criteria have...
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Multimodal Genetic Algorithm with Phase Analysis to Solve Complex Equations of Electromagnetic Analysis
PublikacjaIn this contribution, a new genetic-algorithm-based method of finding roots and poles of a complex function of a complex variable is presented. The algorithm employs the phase analysis of the function to explore the complex plane with the use of the genetic algorithm. Hence, the candidate regions of root and pole occurrences are selected and verified with the use of discrete Cauchy's argument principle. The algorithm is evaluated...
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Solution of coupled integral equations for quantum scattering in the presence of complex potentials
PublikacjaIn this paper, we present a method to compute solutions of coupled integral equations for quantum scattering problems in the presence of a complex potential. We show how the elastic and absorption cross sections can be obtained from the numerical solution of these equations in the asymptotic region at large radial distances.
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A method of determination of electrical conduction mechanisms in complex amorphous materials
PublikacjaA novel approach to determine conduction mechanisms in complex amorphous materials was presented and tested on a real system. In the first step of the presented method, total electrical admittance of the material is analyzed in order to separate a couple of processes, each of which can be described by Jonscher's universal dielectric response. In the following step, a temperature dependence of dielectric response parameters of the...