Wyniki wyszukiwania dla: NEUROFIZJOLOGIA - MOST Wiedzy

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Wyniki wyszukiwania dla: NEUROFIZJOLOGIA

Wyniki wyszukiwania dla: NEUROFIZJOLOGIA

  • Brain and Mind Electrophysiology lab

    Neurofizjologia pamięci i funkcji poznawczych mózgu

  • Unsupervised machine-learning classification of electrophysiologically active electrodes during human cognitive task performance

    Publikacja
    • K. Saboo
    • Y. Varatharajah
    • B. Berry
    • V. Kremen
    • M. Sperling
    • K. Davis
    • B. Jobst
    • R. Gross
    • B. Lega
    • S. Sheth... i 3 innych

    - Scientific Reports - 2019

    Identification of active electrodes that record task-relevant neurophysiological activity is needed for clinical and industrial applications as well as for investigating brain functions. We developed an unsupervised, fully automated approach to classify active electrodes showing event-related intracranial EEG (iEEG) responses from 115 patients performing a free recall verbal memory task. Our approach employed new interpretable...

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  • Combined Single Neuron Unit Activity and Local Field Potential Oscillations in a Human Visual Recognition Memory Task

    Publikacja
    • M. Kucewicz
    • B. Berry
    • M. Bower
    • J. Cymbalnik
    • V. Svehlik
    • S. Stead
    • G. Worrell

    - IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING - 2016

    GOAL: Activities of neuronal networks range from action potential firing of individual neurons, coordinated oscillations of local neuronal assemblies, and distributed neural populations. Here, we describe recordings using hybrid electrodes, containing both micro- and clinical macroelectrodes, to simultaneously sample both large-scale network oscillations and single neuron spiking activity in the medial temporal lobe structures...

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  • Gamma oscillations precede interictal epileptiform spikes in the seizure onset zone

    Publikacja
    • L. Ren
    • M. Kucewicz
    • J. Cymbalnik
    • J. Matsumoto
    • B. Brinkmann
    • W. Hu
    • W. Marsh
    • F. Meyer
    • S. Stead
    • G. Worrell

    - NEUROLOGY - 2015

    OBJECTIVE: To investigate the generation, spectral characteristics, and potential clinical significance of brain activity preceding interictal epileptiform spike discharges (IEDs) recorded with intracranial EEG. METHODS: Seventeen adult patients with drug-resistant temporal lobe epilepsy were implanted with intracranial electrodes as part of their evaluation for epilepsy surgery. IEDs detected on clinical macro- and research microelectrodes...

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  • Dysfunctional prefrontal cortical network activity and interactions following cannabinoid receptor activation.

    Publikacja

    - Journal of Neuroscience - 2011

    Coordinated activity spanning anatomically distributed neuronal networks underpins cognition and mediates limbic-cortical interactions during learning, memory, and decision-making. We used CP55940, a potent agonist of brain cannabinoid receptors known to disrupt coordinated activity in hippocampus, to investigate the roles of network oscillations during hippocampal and medial prefrontal cortical (mPFC) interactions in rats. During...

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  • Human verbal memory encoding is hierarchically distributed in a continuous processing stream

    Publikacja
    • M. Kucewicz
    • K. Saboo
    • B. Berry
    • V. Kremen
    • L. Miller
    • F. Khadjevand
    • C. Inman
    • P. Wanda
    • M. Sperling
    • R. Gorniak... i 8 innych

    - eNeuro - 2019

    Processing of memory is supported by coordinated activity in a network of sensory, association, and motor brain regions. It remains a major challenge to determine where memory is encoded for later retrieval. Here we used direct intracranial brain recordings from epilepsy patients performing free recall tasks to determine the temporal pattern and anatomical distribution of verbal memory encoding across the entire human cortex. High...

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  • High frequency oscillations are associated with cognitive processing in human recognition memory

    Publikacja
    • M. Kucewicz
    • J. Cymbalnik
    • J. Matsumoto
    • B. Brinkmann
    • M. Bower
    • V. Vasoli
    • V. Sulc
    • F. Meyer
    • W. Marsh
    • S. Stead
    • G. Worrell

    - Brain: A Journal of Neurology - 2014

    High frequency oscillations are associated with normal brain function, but also increasingly recognized as potential biomarkers of the epileptogenic brain. Their role in human cognition has been predominantly studied in classical gamma frequencies (30-100 Hz), which reflect neuronal network coordination involved in attention, learning and memory. Invasive brain recordings in animals and humans demonstrate that physiological oscillations...

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  • Evidence for consolidation of neuronal assemblies after seizures in humans

    Publikacja
    • M. Bower
    • M. Stead
    • R. Bower
    • M. Kucewicz
    • V. Sulc
    • J. Cymbalnik
    • B. Brinkmann
    • V. Vasoli
    • E. St.louis
    • F. Meyer... i 2 innych

    - Journal of Neuroscience - 2015

    The establishment of memories involves reactivation of waking neuronal activity patterns and strengthening of associated neural circuits during slow-wave sleep (SWS), a process known as "cellular consolidation" (Dudai and Morris, 2013). Reactivation of neural activity patterns during waking behaviors that occurs on a timescale of seconds to minutes is thought to constitute memory recall (O'Keefe and Nadel, 1978), whereas consolidation...

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  • Pathological and physiological high-frequency oscillations in focal human epilepsy

    Publikacja
    • A. Matsumoto
    • B. Brinkmann
    • S. Stead
    • J. Matsumoto
    • M. Kucewicz
    • W. Marsh
    • F. Meyer
    • G. Worrell

    - JOURNAL OF NEUROPHYSIOLOGY - 2013

    High-frequency oscillations (HFO; gamma: 40-100 Hz, ripples: 100-200 Hz, and fast ripples: 250-500 Hz) have been widely studied in health and disease. These phenomena may serve as biomarkers for epileptic brain; however, a means of differentiating between pathological and normal physiological HFO is essential. We categorized task-induced physiological HFO during periods of HFO induced by a visual or motor task by measuring frequency,...

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  • Dissecting gamma frequency activities during human memory processing

    Publikacja
    • M. Kucewicz
    • B. Berry
    • V. Kremen
    • B. Brinkmann
    • M. Sperling
    • B. Jobst
    • R. Gross
    • B. Lega
    • S. Sheth
    • J. Stein... i 6 innych

    - Brain: A Journal of Neurology - 2017

    Gamma frequency activity (30-150 Hz) is induced in cognitive tasks and is thought to reflect underlying neural processes. Gamma frequency activity can be recorded directly from the human brain using intracranial electrodes implanted in patients undergoing treatment for drug-resistant epilepsy. Previous studies have independently explored narrowband oscillations in the local field potential and broadband power increases. It is not...

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